Objective
The project is an integrated approach of directed toxicological studies and exposure assessments to characterise the emerging human and wildlife health risks from brominates flame retardants (Bars) by endocrine disruption. The project consists of seven themes:
1) Selection of the BFR congeners by in vitro (receptor) assays covering a wide spectrum of endocrine effects;
2) Human hazard identification by studies in rats, including assessment of reproductive and immune function;
3) Aquatic wildlife hazard identification in zebra fish and flounder;
4) Human exposure assessment by measurement of actual levels and time trends in breast milk and human diets in Europe;
5) Aquatic ecosystem exposure assessment by measurement of levels in the aquatic food chain including top predators in polluted and reference sites in Europe;
6) Integrated risk assessment for humans and aquatic wildlife based on data from themes 1-5; and
7) Communication to policymakers, public and industry as basis for preventive action.
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
3720 BA Bilthoven
Netherlands
Participants (18)
40225 Duesseldorf
166 28 Praha 6
171 77 Stockholm
2500 EX Den Haag ('S-gravenhage)
0033 Oslo
1970 AB Ijmuiden
1790 AB Den Burg
0403 Oslo
7491 Trondheim
106 91 Stockholm
67663 Kaiserslautern
1018 WV Amsterdam
Guildford
901 57 Umeaa
97078 Wuerzburg
3584 CL Utrecht
2020 Anvers /Antwerpen
1081 HV Amsterdam