Objective
The project is an integrated approach of directed toxicological studies and exposure assessments to characterise the emerging human and wildlife health risks from brominates flame retardants (Bars) by endocrine disruption. The project consists of seven themes:
1) Selection of the BFR congeners by in vitro (receptor) assays covering a wide spectrum of endocrine effects;
2) Human hazard identification by studies in rats, including assessment of reproductive and immune function;
3) Aquatic wildlife hazard identification in zebra fish and flounder;
4) Human exposure assessment by measurement of actual levels and time trends in breast milk and human diets in Europe;
5) Aquatic ecosystem exposure assessment by measurement of levels in the aquatic food chain including top predators in polluted and reference sites in Europe;
6) Integrated risk assessment for humans and aquatic wildlife based on data from themes 1-5; and
7) Communication to policymakers, public and industry as basis for preventive action.
Fields of science
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
3720 BA BILTHOVEN
Netherlands
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Participants (18)
40225 DUESSELDORF
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166 28 PRAHA 6
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171 77 STOCKHOLM
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2500 EX DEN HAAG ('S-GRAVENHAGE)
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0033 OSLO
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1970 AB IJMUIDEN
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1790 AB DEN BURG
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0403 OSLO
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7491 TRONDHEIM
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106 91 STOCKHOLM
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67663 KAISERSLAUTERN
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1018 WV AMSTERDAM
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GUILDFORD
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901 57 UMEAA
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97078 WUERZBURG
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3584 CL UTRECHT
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2020 ANVERS /ANTWERPEN
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1081 HV AMSTERDAM
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