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Content archived on 2024-05-18

Development and implementation of new 'in vivo' and 'in vitro' systems for the characterisation of endocrine disruptors

Objective

Reliable models for the toxicological testing of hormonally active compounds are essential for the development of safety assessment programmes related to the exposure of animals and humans to endocrine disrupters (Ends). The objective of this project is to develop a transgenic mouse model for the characterization of environmental estrogens. This model will contain all the genetic elements that may provide a rapid, flexible, sensitive, economic and informative system for the toxicological testing and for the hazard identification/risk assessment of Ends. Moreover, from this model, reliable "in vitro" systems will be derived. A new estrogens regulated reporter system will also be constructed for its application to the study of low levels of hormones "in vitro". The economical relevance of our project is attested by the industrial participation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

Data not available

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

THE UNIVERSITY OF MILANO
EU contribution
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Address
Via Festa del Perdono 7
20122 MILANO
Italy

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (3)

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