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Hira nucleosomal assembly pathway related to centromere structure

Objective

HIRA biochemical characterization including its possible partners to examine its physiological relevance in nucleoside assembly mechanisms in vitro. Producing recombinant Venous CENP-A and polyclinic antibodies against such protein, I will examine by immunofluorescence the possible role of HIRA in chromatin assembly that could be involved in the centromeric structure.

Call for proposal

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Coordinator

INSTITUT CURIE
Address
Rue d'ulm 26
75248 Paris
France

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EU contribution
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