Objective
Neuropeptide Y (NPY) is involved in the regulation of a variety of physiological events including pituitary hormone secretion, energy balance, and feeding behavior. The aim of the research project is to study the functional relationship between energy balance, hypothalamic orexigenic NPY and pituitary luteinizing hormone (M) secretion in fish, using the sea bass (Dicentrarchus labrax L.), as the experimental model. Some good evidences have been already found finding that in juvenile sea bass, under negative energetic balance imposed by chronic fasting, LH secretion ""in vivo"" is dose dependently enhanced in response to NPY. These data will be pursued by investigating the mRNA expression and peptides levels of NPY, GnRH (brain gonadotropin-releasing hormone) and LH as well as effects of NPY on LH - GnRS axis under negative or positive energetic balance. This investigation will be screened throughout different periods of starvation, and reproductive stage in male and female sea bass in order to understand possible sexual dimorphism and influences of the sexual cycle in these processes. Finally, the presence of leptin, the product of obesity (ob) gene in mammals, and the functional studies on the effect of leptin on energetic homeostasis, food intake and neuroendocrine function will be investigated.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules
- natural sciences biological sciences zoology mammalogy
- medical and health sciences basic medicine physiology homeostasis
- medical and health sciences health sciences nutrition obesity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
28006 Madrid
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.