Objective
Vitamin C (Ascorbic acid, AA) deficiency is one of the main factors explaining larval fish pathologies and juvenile mortality. Fish species are diversified regarding their vitamin C availability, because AA can be synthesised if the key enzyme, L- gulonolactone oxidase ( GLO ) is active.
This bio- synthetic pathway has been lost at different occasions during the course of evolution. Among the mammals, primates have lost this capacity because the gene coding GLO has accumulated large number of random mutations. In fish, it seems that all teleosts cannot synthetise AA while non teleost taxa have active GLO.
This could be the result of a single evolutionary event. To understand what drives the capacities of fish to synthesise AA, we propose to work on active GLO (bowfin, sturgeon) and non-active teleosts (rainbow trout, medaka), chosen for their phylogenetic links and the availability of molecular tools.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences zoology mammalogy primatology
- social sciences sociology demography mortality
- natural sciences biological sciences genetics mutation
- natural sciences biological sciences zoology ichthyology
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Coordinator
JOUY-EN-JOSAS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.