Objective
Parkinson's disease (PD) is a neurodegenerative illness with high prevalence and long course characterized by severe motor and cognitive impairments. Clinical trials have recently shown that chronic high frequency stimulation (HFS) of sub thalamic nucleus (STN) alleviates Parkinson Ian motor symptoms and elodea-induced complications at advanced stages of PD. However, little is known about the functional mechanisms of this new therapeutically tool, its long-term motor effects and consequences on cognitive functions. The aim of this project is thus to address these issues. Behavioural consequences of STN HFS will be specified in terms of motor and cognitive functions in PD patients and in animal models. Biochemical and cellular events underlying the behavioural effects of STN HFS and neuropath logical factors that may govern its efficacy will be investigated in animal models. The results are expected to have major socio-economic impacts by improving indication of STN HFS in the course of PD.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology cognitive neuroscience
- medical and health sciences basic medicine neurology parkinson
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
13402 MARSEILLE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.