Objective
A striking effect of increasing age, even in health, is progressive muscle weakness. This affects the ability to perform simple, but essential physical tasks and results in less independency and reduced quality of life. Muscle weakness is product of loss of muscle mass and quality. This may be linked to older people having an impaired ability to up-regulate muscle growth factors in response to exercise, which is the only known mean of enlarging muscle contractile content admass, and thus, improving muscle function. However, it is our hypothesis that twill is possible to amplify the growth factor and repair processes with specifically designed nutritional interventions that are targeted at enhancing these specific mechanisms at the transcriptional and transactional levels. Thereby, combined physical training and nutritional supplementation will improve muscle function in the elderly more than can be achieved with either alone.
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
2100 KOEPENHAGEN
Denmark