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Content archived on 2024-05-15

Impact of age-related brain white matter changes on transition to disability in the elderly. leukoaraiosis and disability.

Objective

Age-Related White Matter Changes (ARWMC) of brain is associated with cognitive, motor and psychopathological disturbances, all related to disability in the elderly. The aim is to evaluate ARWMC as independent determinant of transition to disability in the elderly. Subjects with ARWMC of different severity and no/mild disability will be followed for 3 years, evaluating transition to disability, death, stroke, dementia, depression and progression of ARWMC on repeat MRI. Relative risks of transition and other outcomes will be calculated in the different ARWMC severity groups, adjusting for other determinants of disability in the elderly. Transactional harmonisation of clinical and Reassessments of ARWMC will be also delivered.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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Funding Scheme

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CON - Coordination of research actions

Coordinator

UNIVERSITY OF FLORENCE
EU contribution
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Address
Viale Morgagni 85
50134 FIRENZE
Italy

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Total cost

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Participants (13)

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