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Content archived on 2024-05-18

Ageing-related muscle wasting: causes, prevention and reversal

Objective

Weakening of skeletal muscle during ageing decreases quality of life, frequently leads to falls, institutlonalization or physical dependency in the elderly and poses a serious social and economic problem for the EU (estimated costs > euro 10^10 annually). Both loss of muscle mass (atrophy) and altered muscle function contribute to ageing-related weakening. Reasons for either of these changes are complex and unclear, but studies have shown that exercise can enhance muscle mass in the elderly. This proposal establishes A TRONET, a group of basic and clinical researchers, whose aim is to understand the reasons for atrophy in ageing muscle and the mechanisms by which it can be reversed. Expected outcomes of the work are
a) definition of changes occurring in ageing muscle that cause atrophy,
b) indications of how individuals may vary in their propensity to ageing-related muscle weakening,
c) unimproved understanding of the potential routes to mitigation of ageing-related muscle weakening.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

MEDICAL RESEARCH COUNCIL
EU contribution
No data
Address
New Hunts House, 4th Floor South, Guy's Campus, Ki
SE1 1UL LONDON
United Kingdom

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (5)

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