Objective
The problem of the aging population is a worldwide phenomenon and it is also acute in Europe. Greater understanding of treatment of Parkinson's Disease (PD) and Psychoses (striking young people particularly) will be a major contribution to the quality of life in Europe. The proposed research of the dopaminergic Partial Agonist concept is likely to deliver new clinical treatment against PD and new atypical anti-psychotics with an improved side-effect profile. Axon Biochemical's BV and Arid Carlson Research AB will work together with a third SME in order to develop the dopamine partial agonist GMC1111 to the stage of "proof of principle". At this stage the three Sees will after the project, which needs further costly development in order to become a new drug, to the drug industry worldwide. GMC1111 represents a new therapeutic approach, based on proof. Ardí Calzón's DA auto receptor concepta. The objectives will be achieved by National phase applications of the patent application of GMC1111, SAR and lead optimisation large scale synthesis, a toxicological study, a check of safety and pharmacokinetics, and a Phase II study in a limited number of patients.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- medical and health sciences basic medicine pharmacology and pharmacy pharmacokinetics
- medical and health sciences basic medicine neurology parkinson
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
9721 WN GRONINGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.