Objective
The objective of the present project is to decipher basic cellular and molecular processes that underlie disturbances in the control of biological rhythms withageing. The suprachiasmatic nucleus (SCN) plays a role of biological clock and is unique for studies of ageing phenomena at the cellular and molecular level that can be correlated to a distinct function, the regulation of biological rhythms, which undergoes major changes with ageing to deteriorate the quality of life. Despite the clinical evidence that biological rhythms are disrupted in elderly people, little is known about the molecular, cellular and functional changes occurring in the SCN with ageing. In the proposed project we will study changes of factors intrinsic to the neurons in the SCN as well as extrinsic factors in humans and experimental systems. The latter includes effects on the SCN by cytokines that increase in the blood and the brain in awed individuals.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
171 77 STOCKHOLM
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.