Objective
Two white adipose tissue hormones, adiponectin and lepton, limit entopic lipid accumulation. In obesity adiponectin levels drop and lepton levels increase and lepton "insensitivity" occurs, resulting in entopic lipid accumulation and type 2 diabetes and cardiovascular disease and low levels of growth hormone perpetuating obesity. Thus, we will evaluate lepton receptor (Ob-Rib) function together with adiponectin concentrations as prognostic/diagnostic tools for the development of age related obesity and diseases. Conjugated linoleum acids (Class) and polyunsaturated fatty acids (n-3 Pupas) can decrease entopic lipid and we will evaluate their use in combination, as a natural and novel therapeutic agent to counter obesity related disease. Abdominal WAT is causative in obesity related disease. We will compare differences between abdominal WAT and other depots to identify further mechanisms in obesity related disease.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences theoretical physics particle physics leptons
- medical and health sciences clinical medicine endocrinology diabetes
- natural sciences biological sciences biochemistry biomolecules lipids
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences health sciences nutrition obesity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
AB21 9SB ABERDEEN
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.