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Rapid stroke marker detection via immunosensors utilising labeless electrochemical and resonant mass detection, step 2 of EXAW-1999-01799

Objective

Stroke is the third most common cause of death and the leading cause of morbidity and long-term disability. The use of thrombolytic therapy such as that of tissue plasminogen activator MUST be administered within three hours of stroke onset to be effective in reversal/reduction of stroke injury. The objective of this project is to develop an individually addressable array of labeless affinity biosensors for the rapid detection of biochemical and neurochemical markers for stroke, facilitating the rapid diagnosis essential for introduction of thrombolytic therapy. Labeless affinity sensors integrated with sample manipulation on a disposable microsystem platform address the problem associated with rapid diagnosis of stroke by allowing cost-effective (typically 10 EURO), rapid (in minutes), specific (using novel monoclonal antibodies and aptamers) and sensitive (ng-pg/ml), detection of stroke markers for use at the point-of-care.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

CANAG DIAGNOSTICS AB
Address
Majnabbe Terminal Building
414 55 Goeteborg
Sweden

Participants (8)

CRANFIELD UNIVERSITY*
United Kingdom
Address
Wharley End
MK43 0AL Cranfield,bedford
ECO CHEMIE BV
Netherlands
Address
Kanaalweg 29G
3526 KL Utrecht
INSTITUT CATALA DE LA SALUT
Spain
Address
Paseo Valle De Hebron 119-129
08035 Barcelona
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Address
Universite Victor Segaien, 146 - Rue Leo Saignat
33076 Bordeaux
INTERUNIVERSITAIR MIKRO-ELEKTRONICA CENTRUM VZW
Belgium
Address
Kapeldreef 75
3001 Heverlee
MICROARRAY LTD
United Kingdom
Address
Grosvenor Street
M1 7HS Manchester
UNIVERSITAT ROVIRA I VIRGILI
Spain
Address
Avinguda Dels Paisos Catalans 26
43007 Tarragona
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
Address
Lee Maltings, Prospect Row
Cork