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Content archived on 2024-05-27

Determination of macromolecular crystal structures: integrated, automated and user-friendly approaches

Objective

X-ray crystallography continues to expand very rapidly and there are 100s of laboratories in academia and industry. This expansion will increase in response to genome based structural programmes. This proposal provides the growing community (often relatively inexperienced) with the crystallographic tools to meet the technically advanced demands of modern structural biology. The aim is to bring together major European crystallographic software groups to design, implement and support a framework for computational crystallography - namely, data processing, phase determination, refinement, validation and deposition of structural data. Twill address the problems often present in crystals with very large cells, complex assembly or unstable contents and lattice defects. It will involve the development of software for high throughput structure solution. This is an urgent requirement to handle the expected output of the genome projects.

Call for proposal

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Coordinator

UNIVERSITY OF YORK
EU contribution
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Address
University Road
YO1 5DD YORK
United Kingdom

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Total cost
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Participants (8)