Follicle stimulating hormone (FSH) is also a pituitary glycoproteic hormone. It acts synergetically with LH to control gonadal functions. High concentrations of FSH in plasma would suggest gonadal failure in both males and females. FSH and LH are structurally very close.
The aim of this project is identical to that on LH and it should proceed along the same lines.
In 1988 an interlaboratory trial was organised involving 22 laboratories, to determine FSH in different serum samples. The results showed a marked difference in means between the all radioimmunoassay (RIA) and the all immunometric assay (IMA) groups. This suggests that the all laboratory trimmed mean (ALTM) is unlikely to provide a suitable target value, at least for high concentration of FSH. Work may continue with epitope mapping studies such as those carried out for LH when the studies on the latter are completed.
Funding SchemeCSC - Cost-sharing contracts
EH3 9YW Edinburgh
65926 Frankfurt Am Main
EN6 3QG Potters Bar