HUMAN FOLLICLE STIMULATING HORMONE

Objective

Follicle stimulating hormone (FSH) is also a pituitary glycoproteic hormone. It acts synergetically with LH to control gonadal functions. High concentrations of FSH in plasma would suggest gonadal failure in both males and females. FSH and LH are structurally very close.
The aim of this project is identical to that on LH and it should proceed along the same lines.

STATUS

In 1988 an interlaboratory trial was organised involving 22 laboratories, to determine FSH in different serum samples. The results showed a marked difference in means between the all radioimmunoassay (RIA) and the all immunometric assay (IMA) groups. This suggests that the all laboratory trimmed mean (ALTM) is unlikely to provide a suitable target value, at least for high concentration of FSH. Work may continue with epitope mapping studies such as those carried out for LH when the studies on the latter are completed.

Programme(s)

• FP2-BCR 4 - Research and development programme (EEC) in the field of applied metrology and chemical analysis (Community Bureau of Reference - BCR), 1988-1992

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

Akademisch Ziekenhuis

Address

Brussel
Belgium

Participants (31)

BioMérieux SA

France

Address

Marcy L'etoile
69260 Charbonnières-les-bains

Bleuland Ziekenhuis

Netherlands

Address

Gouda

Boehringer Mannheim GmbH

Germany

Address

Penzberg

Cliniques Universitaires St Luc

Belgium

Address

Bruxelles

Copenhagen County Hospital

Denmark

Address

Glostrup

Dakopatts

Denmark

Address

Glostrup

Edinburgh Royal Infirmary

United Kingdom

Address

EH3 9YW Edinburgh

Eurogentec S.A.

Belgium

Address

Liège

HANNOVER MEDICAL SCHOOL

Germany

Address

Carl-neuberg-strasse 1
30625 Hannover

Hoechst AG

Germany

Address

Brüningstraße
65926 Frankfurt Am Main

Hospital de la Santa Creu i San Pau

Spain

Address

Barcelona

Hybritech Europe

Belgium

Address

Liège

INSTITUT GUSTAVE ROUSSY

France

Immunotech SA

France

Address

130 Avenue De Lattre De Tassigny
13009 Marseille

Institut des Radioéléments-Medgenix

Belgium

Address

Fleurus

Klinikum München-Großhadern

Germany

Address

Marchioninistraße 15
81377 München

Laboratoires d'Analyses Biologiques Spécialisées

France

Address

Nice

Medizinische Universität Lübeck

Germany

Address

Ratzeburger Allee 160
23562 Lübeck

National Athletic Research Centre

Greece

Address

Athens

National Institute for Biological Standards and Control (NIBSC)

United Kingdom

Address

Blanche Lane South Mimms
EN6 3QG Potters Bar

Novo Biolabs Ltd.

United Kingdom

Address

Cambridge

Nuclear Research Centre Demokritos

Greece

Address

Athens

ORIS-Industrie

France

Address

Bagnols-sur-ceze

SERATEC Gesellschaft für Biotechnologie mbH

Germany

Address

Rudolf-winkel-straße 1A
37079 Göttingen

Serono Diagnostics Ltd.

United Kingdom

Address

Woking

Sorin Biomedica SpA

Italy

Address

Salluggia

St Thomas's Hospital

United Kingdom

Address

London

St. Radboud Ziekenhuis Nijmegen

Netherlands

Statens Seruminstitut

Denmark

Address

Copenhagen

Universidade de Coimbra

Portugal

Université d'Aix-Marseille II

France

Address

13288 Marseille