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Content archived on 2024-04-16

SULPHADIMIDINE IN PIG KIDNEY, LIVER AND MUSCLE RMs

Objective


The objective of the project was to prepare samples of pig muscle, liver and kidney from animals treated with sulphadimidine or never treated with sulphadimidine. Collaborative work between major national laboratories to improve methods and results has been undertaken. Stability studies of liver reference materials (RM) with additives were successful completed, and optimized lyophilization and irradiation conditions have been established. Preparation of preliminary batches of muscle and kidney RMs has been carried out.
The project is one of a series initiated at the request of the Commission's Agricultural Services (DG VI) to provide RMs in support of Community Policy banning the use of growth promoting compounds in farm animals and the Directive laying down requirements for monitoring of undesirable substances in farm animals and products in Member States (86/469/EEC).

Sulphadimidine is a member of the sulphonamide group of drugs. It is a broad spectrum antibiotic widely used in animal production either alone or in combination with other sulphonamides and antibiotics. It has a bacteriostatic action but when combined with trimethoprim, it produces a synergic effect which is both bacteriostatic and bactericidal.
Its use has been widely detected in farm animals with a significant percentage of pigs having residues in excess of the tolerance of 0.1 mg/kg. It is the drug with the highest number of violations of the directive 86/469/EEC. It is routinely monitored in Member States with the National Monitoring Programs. Monitoring is primarily in meat and offal.

The objective of the project is to prepare sample of pig muscle, liver and kidney from animals:
- treated with sulphadimidine
- never treated with sulphadimidine.
Collaborative work between the major national laboratories to improve methods and results will be undertaken.

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Funding Scheme

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Coordinator

Veterinary Science Division
EU contribution
No data
Address
Stoney Road Stormont
BT4 3SD Belfast
United Kingdom

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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