Objective
Oestradiol is a C18-steroid and is found in both females and males. In females, throughout puberty, it stimulates growth of the sex organs and development of secondary sexual characteristics, while in adult females its main biological action is on the functioning of the reproductive tract. In the male the role of oestradiol is thought to be involved with testosterone in the regulation of gonadotrophin secretion. Oestradiol assay is the most widely used test for the assessment of oestrogen status in infants and adults. Oestradiol analysis is also essential for monitoring ovulation inducing therapies and hormone replacement after castration or in the post-menopausal period of life.
The project aims at the certification of 17beta-oestradiol concentrations in human serum materials, by method procedures using isotope dilution - mass spectrometry (ID-MS).
STATUS
The feasibility of preparation and conservation of human serum based samples was sucessfully demonstrated. The method development achieved allows to envisage a certification exercise in 1992.
The project is actually at the stage of collecting the required human sera. Certification is expected in 1993 - 1994.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
501 Firenze
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.