The common methods for the personal monitoring of the exposure of workers to isocyanates in workplace air uses sampling through solids or liquids containing a reagent such as 1-(2-methoxyphenyl)-piperazine (2-MP) which reacts with the isocyanates to form stable compounds which are then determined by HPLC. It is difficult for laboratories to check if they meet the planned CEN requirement of 30 % overall accuracy; no sufficiently validated methods or reference materials exist.
Intercomparisons will therefore be organised in which simulated evaporation residues of 2-MP sampling solutions will be distributed. Reference materials will be certified (simulated evaporation residues of sampling solutions, and pure substances). The analytes of interest will be: 2,4- and 2,6-toluene diisocyanate (TDI), 4,4'-diphenyl-methane diisocyanate (MDI) and hexamethylene diisocyanate (HDI).
Feasibility study (preparation of pure and homogeneous batches; study of stability upon long term storage) in progress.
Funding SchemeCSC - Cost-sharing contracts
53757 Sankt Augustin
TW16 7LN Sunbury On Thames
EH8 9SU Edinburgh