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ISOCYANATES IN WORKPLACE AIR

Objective



The common methods for the personal monitoring of the exposure of workers to isocyanates in workplace air uses sampling through solids or liquids containing a reagent such as 1-(2-methoxyphenyl)-piperazine (2-MP) which reacts with the isocyanates to form stable compounds which are then determined by HPLC. It is difficult for laboratories to check if they meet the planned CEN requirement of 30 % overall accuracy; no sufficiently validated methods or reference materials exist.

Intercomparisons will therefore be organised in which simulated evaporation residues of 2-MP sampling solutions will be distributed. Reference materials will be certified (simulated evaporation residues of sampling solutions, and pure substances). The analytes of interest will be: 2,4- and 2,6-toluene diisocyanate (TDI), 4,4'-diphenyl-methane diisocyanate (MDI) and hexamethylene diisocyanate (HDI).

STATUS

Feasibility study (preparation of pure and homogeneous batches; study of stability upon long term storage) in progress.

Coordinator

AKZO Corporate Res.
Address

Arnhem
Netherlands

Participants (26)

Arbetsmiljoeinstitutet
Sweden
Address

Umea
BASF AG
Germany
Address
Kaiser-wilhelm-straße 52
67059 Ludwigshafen
BIA
Germany
Address

53757 Sankt Augustin
BP International Ltd
United Kingdom
Address
Chertsey Road
TW16 7LN Sunbury On Thames
Bayer AG
Germany
Address
Kaiser-wilhelm-allee 2
51373 Leverkusen
Dansk Teknologisk Inst.-Kemiteknik
Denmark
Address

Aarhus
Directoraat-Generaal van de Arbeid
Netherlands
Address

Den Haag
EOLAS
Ireland
Address

Dublin
Fondazione Clinica del Lavoro
Italy
Address

271 Pavia
Friedrich-Alexander-Universität Erlangen Nürnberg
Germany
Address
Schillerstraße 25 Und 29
91054 Erlangen
Health and Safety Executive (HSE)
United Kingdom
Address

London
INSHT
Spain
Address

Madrid
INSHT
Spain
Address

Barcelona
INSTITUT NATIONAL DE L'ENVIRONNEMENT INDUSTRIEL ET DES RISQUES
France
Address
Parc Technologique Alata
Verneuil En Halatte
Imperial Chemical Industries plc (ICI)
United Kingdom
Address

Manchester
Inst. Milieuwetenschappen TNO
Netherlands
Address

Delft
Inst. Nac. de Saude Dr Ricardo Jorge
Portugal
Address

Porto
Inst. Univ. de Medicine et d'Hygiene du Travail
Switzerland
Address

Lausanne
Institut Gefahrstoffforschung der Bergbau-Berufsgenossenschaft
Germany
Address

Bochum
Institut National de Recherche et de Securite
France
Address
Avenue De Bourgogne
54501 Vandoeuvre-les-nancy
Institute of Occupational Medicine
United Kingdom
Address
8 Roxburgh Place
EH8 9SU Edinburgh
Miljoe-Kemi
Denmark
Address

Galten
Min. Emploi et Travail
Belgium
Address

Brussels
Rhône-Poulenc Industrialisation SA
France
Address
24 Avenue Jean Jaurès
69151 Décines-charpieu
Tampere Regional Inst. of Occup. Health
Finland
Address

Tampere
Turku Regional Inst. of Occupational Health
Finland
Address

Turku