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Content archived on 2024-04-16

BLOOD GROUPING REAGENTS

Objective



The safety of blood transfusion in the European Community relies in part on the quality of the reagents used for ABO and Rh(D) typing and compatibility testing. Mistyping of donors or patients caused by defective substandard reagents can lead to clinically significant transfusion reactions, and in some cases, fatality. There are no European reference materials available for the control of the quality of the reagents in use.

The aim of this project is to prepare, with the collaboration of representatives from blood transfusion laboratories and reagent manufacturers operating within Europe, anti-A, anti-B and anti-D certified reference materials. The certification will be conducted according to agreed specifications and will include the evaluation, validation and stability study of the proposed materials. Similar work may then be envisaged for three additional standards (anti-IgG, papain and control weak anti-D and red cell panels for anti-D evaluation).

STATUS

Candidate pilot freeze-dried materials for anti-A, anti-B and anti-D are being tested and compared to existing FDA and WHO standards by the participants. The results are expected to be reported by mid 1992. Certification to be completed in 1993.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

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Call for proposal

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

International Blood Group Reference Laboratory
EU contribution
No data
Address

BS Bristol
United Kingdom

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (22)

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