Objective
Some fundamental questions concerning structures and functions of melanins, including neuromelanin, have been attacked. New approaches were developed and applied to investigations on the structures of melanins by nondestructive methods. This led to the identification of novel structural elements and a revised mechanism of biosynthesis. Furthermore, new insights into the mechanisms of action of important neurotoxins were gained.
The work is of particular significance for future investigations on the molecular aspects of Parkinson's disease (PD) in connection with the role of neuromelanin (NM). PD is a neurological disorder affecting primarily the elderly. It is estimated that in Europe approximately 20 to 30 out of 1000 of those over the age of 60 will develop the symptoms of Parkinsonism. In coming years, PD will probably even become more frequent because of the general increase of human life span. Thus, Parkinsonism is an increasing public health problem, and the enormous social and economical impact of PD is quite obvious.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- medical and health sciences basic medicine neurology parkinson
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
53121 BONN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.