Benzoic acid - a model system for proton tunneling dynamics

Objective

The proposal initiates between two laboratories a collaborative research project on proton tunneling dynamics in intermolecular hydrogen bonds. Initially, benzoic acid doped with dyes of
systematically varied polarity will be investigated intensively using frequency high-resolution and time-resolving picosecond sectroscopy. The understanding of this model system is expected to lead to a conceptual framework allowing to treat the more complex biological structures. The present study is in particular relevant for the issue of the displacement of tautomeric equilibria in the DNA replication process under the action of mutagens. It is the objective of the collaborative effort to bring to bear the
results of this work in the area of DNA replication by organizing regular joint workshops with the participation of international outside experts.

Fields of science

• natural sciences › chemical sciences › organic chemistry › organic acids
• natural sciences › biological sciences › genetics › DNA

Programme(s)

• FP2-SCIENCE - Programme plan (EEC) to stimulate the international cooperation and interchange needed by European research scientists (SCIENCE), 1988-1992

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

Heinrich-Heine-Universität Düsseldorf

Address

Universitätstraße 1
40225 Düsseldorf
Germany

Links

Participants (1)

UNIVERSITE JOSEPH FOURIER - GRENOBLE 1

France

Address

Rue De La Physique 121-140 Domaine Universitaire
38041 Grenoble

Links