Objective
Fluoresczently labelled molecules are widely used in analytical measurements on account of the very high sensitivity which can be achieved in favourable circumstances. In particular, fluorescent labels are becoming important as replacements for radioisotopes in a variety of applications. The ultimate sensivity of such measurements depends on the ability to eliminate interferences from background fluorescence andscattered light. One very effective means to achieve this sensitivity is to use fluorescent lables with long emissive lifetimes, which can readily be distinguished from short-lived background emission. Recently developed technology has simplified lifetime-resolved fluorescence measurements to a level where these can be used routinely in analytical measurements. Unfortunately, many labels with long fluorescence lifetimes are particularly susceptible to fluorescence quenching by environmental influences. To avoid this we propose to develop a novel time-resolved fluorescence detection system designed for use with specially developed surface-engineered fluorescent labels of near-colloidal size. Such nanoparticles provide a protective matrix within which fluorescent species of long lifetime emit with very high efficiency. The proposed technology would expand the analytical applications of lifetime-resolved fluorescence detection. In addition, the nature of the measurement allows very low cost solid-state excitation and detection systems to be used in a compact format while maintaining very high sensitivity.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences optics microscopy fluorescence lifetime imaging
- engineering and technology nanotechnology nano-materials
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
M6 6AP Tec Salford
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.