Objective
Cells modulate progression through various stages of growth by producing regulatory factors. While a number of positive growth factors are well characterised, little is known, with the exception of interferons, of factors which exert a negative control on cell proliferation. The aim of our work has been to search for, identify, isolate and produce negative effectors of cell replication both for basic studies and for potential pharmacological application.
A 12,500 dalton N.W. protein with potent growth inhibitory activity has been identified, isolated and partially sequenced. A new interferon (IFN) with greater cell inhibitory potency than other IFN species has also been identified and is being isolated. The planned operation includes preparation of both natural and recombinant proteins, structural analysis and biological efficiency; gene cloning and engineering of high efficiency genetic constructs; receptor isolation and methods of signal transduction; biochemical and molecular mechanisms of action.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
SE1 7EH London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.