A COMPLETE PHYSICAL MAP OF THE DROSOPHILIA MELANOGASTER GENOME

Objective

We are proposing to compile a complete physical (molecular) map of the genome of Drosophila melanogaster. This will entail the "fingerprinting" of ca. 30000 DNA fragments (each 30-40 kbasepairs; cloned in a cosmid vector) and their assembly into an ordered array. The project will follow the methods developed in the pioneering work of Sulston and collaborators on Caenorhabditis elegans, and will also take advantage of a special feature of flies, the polytene chromosomes. The physical map wil be integrated with available genetic and cytogenetic information into a Database, which, together with the ordered cosmid library, will be of enormous value to all Drosophila workers.

Programme(s)

• FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

Foundation for Research and Technology-Hellas

Address

71110 Heraklion-crete
Greece

Participants (2)

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

United Kingdom

Address

Trinity Lane, The Old Schools,
CB2 1TN Cambridge

University of Dundee

United Kingdom

Address

The Nethergate
DD1 4HN Dundee