Skip to main content

A COMPLETE PHYSICAL MAP OF THE DROSOPHILIA MELANOGASTER GENOME

Objective



We are proposing to compile a complete physical (molecular) map of the genome of Drosophila melanogaster. This will entail the "fingerprinting" of ca. 30000 DNA fragments (each 30-40 kbasepairs; cloned in a cosmid vector) and their assembly into an ordered array. The project will follow the methods developed in the pioneering work of Sulston and collaborators on Caenorhabditis elegans, and will also take advantage of a special feature of flies, the polytene chromosomes. The physical map wil be integrated with available genetic and cytogenetic information into a Database, which, together with the ordered cosmid library, will be of enormous value to all Drosophila workers.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

Foundation for Research and Technology-Hellas
Address

71110 Heraklion-crete
Greece

Participants (2)

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
Address
Trinity Lane, The Old Schools,
CB2 1TN Cambridge
University of Dundee
United Kingdom
Address
The Nethergate
DD1 4HN Dundee