Objective The overall aim of this twinning project is to investigate the mechanisms of catabolite repression control in the life cycle of representative gram negative bacteria. Specific objectives will be: 1) To investigate the regulation of the E. coli adenyl cyclase (cya) gene at the molecular level with particular emphasis on carbon mediated regulation. 2) To investigate the organisation, regulation and role of the genes involved in cAMP synthesis in Rhizobium meliloti. As we have demonstrated that these organisms contain at least two cya like genes, particular emphasis will be placed on the relative comparison of these systems to the situation in enteric bacteria (i.e. collaborative twinning project between Cork and Paris labs specializing in these areas). 3) To investigate the nature of cAMP synthesis control and catabolite repression control in Rhizobium (using hydrogen metabolism (Hup) as a model system) by host plant signals during the plant-microbial symbiotic interaction involving collaboration between Cork, Montepellier, Madrid and Paris). Fields of science natural sciencesbiological sciencesmicrobiologybacteriology Programme(s) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Topic(s) Data not available Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK Address Western road, presentation buildings 30 Cork Ireland See on map EU contribution € 0,00 Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all INSTITUT PASTEUR France EU contribution € 0,00 Address Rue du docteur roux 25 75724 Paris See on map Institut National de la Recherche Agronomique (INRA) France EU contribution € 0,00 Address 147 rue de l'université 75341 Paris See on map UNIVERSIDAD POLITECNICA DE MADRID Spain EU contribution € 0,00 Address Av. ramiro de maeztu 7 s/n 28040 Madrid See on map
