Objective
The objective is to develop and apply analytical methods for the identification of populations and individuals exposed to selected pesticides and to evaluate levels of exposure.
This project deals with the development and application of analytical methods to identify people exposed to pesticides (professional exposure) and the evaluation of the levels of their exposures. A range of methodologies, both biological and chemical, will be utilized in order to evaluate the most adequate techniques to be applied in relation to pesticide residues or to their metabolite residues.
Exposed professional groups are identified and analyzed in the regions of Campania (Italy), Liguria (Italy), Maresme (Spain), and Helsinki (Finland). The techniques to be applied or developed, are the following.
Biological methods: chromosome aberrations (CA); sister chromatid exchanges (SCE); micronuclei (MN); poly(adenosine diphosphate (ADP) ribose) polymerase (POL); urine analyses (UA); and cholinesterase.
Chemical methods: deoxyribonucleic acid (DNA) adducts; haemoglobin amino acids adducts; and plasma proteins adducts.
All these techniques are also applied to the model animals groups exposed to pesticides, on which the same effects and the metabolism of some pesticides will be investigated.
Pesticides to be analyzed are; thiocarbamates, dibromoethane, dichloroethane, 1,3-dichloropropene, methylisothiocyanate, methylbromide, atrazine, molinate, organophosphate insecticides, alachlor, Chlordimeform, vinclozolin, amitrole, ethylbromide, ethylene oxide, and methyl parathion. For each one of these pesticides a review of their known toxicological potential will be prepared.
Samples from a group of around 3000 unexposed people already participating in a large biomonitoring programme undertaken during the last 5 years for clinical end points will be analyzed as controls.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences organic chemistry aliphatic compounds
- natural sciences chemical sciences organic chemistry amines
- natural sciences biological sciences genetics chromosomes
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
56123 Pisa
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.