Objective The UNCOVER project is a direct contribution to overcome non-publication of clinical studies that have been designed and executed as randomized controlled trials (RCTs). RCTs provide the best utility as input to systematic medicinal reviews, one cornerstone of evidence-based medicine. That is provided that, and only then, RCTs are both correctly registered and published at least once. Because non-publication, as well as publication with time delay of RTCs, can decisively reduce the advantage of such systematic reviews of drugs, medical devices or procedures, it affects the knowledge base, patient value, and level of public health. UNCOVER’s aim is three-fold: 1) to apply established and develop novel, solid, and useful methods for fact-finding and interventions into the socio-economic system defined by causes and sources of the publication bias; 2) to engage with stakeholders and identify strategies, barriers, and facilitating factors associated with the publication bias and its consequences; and 3) to synthesize lessons learned and recommend feasible measures to deal with the publication bias. In a perspective way, this project contributes pro better allocation of funds to sponsor studies and patient value, and contra duplication of work and patients risk. The issues of the publication bias are treated with quantitative, qualitative and participatory means (including tools such as stakeholder maps, institutional analysis, case studies, systematic reviews, interviews, bibliometric analysis and software) in an interdisciplinary approach in areas with little or no lines of evidence as to how they perform in practice. UNCOVER will thus both provide viable solutions for the publication bias, for better allocation efficiency of medicinal and health related research funds, and develop methodologies for future bias research efforts. Fields of science natural sciencescomputer and information sciencessoftwaremedical and health scienceshealth sciencespublic health Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2011.4.1-2 - Targeting publication bias Call for proposal FP7-HEALTH-2011-single-stage See other projects for this call Funding Scheme CSA-SA - Support actions Coordinator AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH EU contribution € 277 592,84 Address GIEFINGGASSE 4 1210 Wien Austria See on map Region Ostösterreich Wien Wien Activity type Research Organisations Administrative Contact Felix Schröpfer (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAT FUR WEITERBILDUNG KREMS Austria EU contribution € 147 818,00 Address DR KARL DORREK STRASSE 30 3500 Krems See on map Region Ostösterreich Niederösterreich Waldviertel Activity type Higher or Secondary Education Establishments Administrative Contact Edith Huber (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL United States EU contribution € 73 391,00 Address "AIRPORT DRIVE 104 SUITE 2200 CB #1350" 27599 Chapel Hill See on map Activity type Higher or Secondary Education Establishments Administrative Contact Tony G. Waldrop (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data