Objective
"Cancer is one of the leading causes of death in the world, taking an enormous toll on the society. Early detection is paramount for effective treatment. Afterwards, to individualize and optimize the treatment regime, it is increasingly becoming evident that early and frequent monitoring of the evolution of the tumour physiology in response to treatment is needed. Optical tools are emerging as promising modalities to this end. We will take advantage of this ability to carry out a pilot study to investigate the possibility of extending the use of diffuse optical methods to aid thyroid cancer characterization and therapy monitoring. Thyroid nodules are very common (~27% in adults) and a considerable amount of these, about 5%, develop into cancers. Unfortunately, the sensitivity and specificity of currently used technique for detection of potentially malignant nodules, thyroid ultrasound (US)-guided biopsies, is poor, making diagnosis and treatment difficult. We believe that optical methods will improve this. Furthermore, malignant tumours usually attract the formation of new and chaotic blood vessels via a complex process called angiogenesis. This has been exploited by the development of numerous treatment methods that rely on the inhibition of angiogenesis. However, it has also been observed that despite initial successful inhibition of angiogenesis, tumours may adapt and regain angiogenesis so that they can grow again. We will investigate this onset of tumour resistance by developing a novel, new 3D optical scanner for diffuse optical spectroscopy (DOS) and diffuse correlation spectroscopy (DCS) in mouse models. If we are successful, we would advance the frontiers on basic understanding of cancer biology and explore new clinical applications of optical technologies."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology
- medical and health sciences basic medicine physiology
- natural sciences physical sciences acoustics ultrasound
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
08860 Castelldefels
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.