Objective
The aim of this project is to design a stem cell-based therapy to prevent end-stage renal disease caused by reflux nephropathy in children. The two main reasons to focus on this condition are that it is the major cause of kidney failure in children and young adults and secondly, the disease typically takes several years to reach end stage, allowing time for therapies to repair damage kidneys before they become completely non-functional. Recent advances in stem cell science and tissue engineering present an unprecedented opportunity to design a stem cell therapy for this clinical problem.
This project will investigate the properties of several different stem cell types (embryonic stem cells, kidney stem cells, amniotic fluid stem cells and mesenchymal stem cells) in order to determine which is most appropriate for the generation of functional kidney tissue. To do this, novel biomaterials will be designed that will provide a substrate both for the generation of kidney progenitor cells and for their transplantation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine nephrology
- medical and health sciences medical biotechnology tissue engineering
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences clinical medicine transplantation
- engineering and technology industrial biotechnology biomaterials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LIVERPOOL
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.