Project description
Virtual Physiological Human
The past decade has seen a revolution in radiation therapy technology, offering exceptional flexibility in dose delivery. Image guidance during treatment ensures a reliable targeting of the dose to the tumor. This has created the possibility to irradiate the tumor with a high dose with minimal exposure of surrounding tissue. Thus an improvement in tumor control is no longer invariably associated with an increase in radiation-induced toxicity.Now the capacity exists to create treatment plans that are tailored to the specific characteristics of the patient. Thus, the success of radiotherapy depends on proper personalized therapy planning and outcome prediction. However, an individualized representational model that informs on radiation therapy planning and outcome prediction is still lacking.There are several modeling approaches available that have the potential to fill this gap, among them empirical, but established radiobiological models and more sophisticated multi-scale models.DR THERAPATs aim is to create the Digital Radiation Therapy Patient, integrating the available knowledge on tumor imaging, image analysis and interpretation, radiobiological models and radiation therapy planning into a reusable, multi-scale digital representation. DR THERAPAT will enable 1) Broad access to dose painting 2) Individualized planning resulting in more effective and safer treatment 3) Accurate prediction of Tumor Control Probability and Normal Tissue Complication Probability, 4) improve outcome, 5) provide a platform demonstrating the integration of modeling into the clinical workflow, and 6) provide a platform for the validation of the models.A demonstrator of this platform will be made for prostate cancer. With a second demonstrator for cervical cancer, we will show that the model can be translated to other forms of cancer. DR THERAPAT will adapt and integrate today's available tools into a digital representation of the patients health status and clinical workflow.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine oncology prostate cancer
- humanities arts visual arts
- social sciences political sciences political transitions revolutions
- medical and health sciences clinical medicine oncology cervical cancer
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-ICT-2011-9
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
22335 Hamburg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.