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Content archived on 2024-06-18

Adaptations of the ATP synthesis machinery in bacteria and archaea to conditions of extreme<br/>energy limitation in the deep subsurface

Objective

Microbes in the deep sub-seafloor have recently been found to survive under unprecedented conditions of extreme energy limitation. I aim to identify microbes in these deep subsurface communities with central energy metabolism that is adapted to these conditions. A combination of single-cell genomics and metagenomics will be used to identify members of the microbial community adapted to low energy flux by use of Na+-based chemiosmotic ATP synthesis. Following sequencing, genes encoding c subunits of the ATP synthase from the deep subsurface will be synthesized and expressed in E. coli to determine ATP synthase c ring stoichiometry. This project represents a novel approach to microbial ecology and physiology in energy-limited environments with a framework that combines state-of-the-art biogeochemistry, molecular microbial ecology, and biochemistry.

Fields of science (EuroSciVoc)

Topic(s)

Call for proposal

FP7-PEOPLE-2013-IIF
See other projects for this call

Funding Scheme

MC-IIF - International Incoming Fellowships (IIF)

Coordinator

AARHUS UNIVERSITET
EU contribution
€ 221 154,60
Address
NORDRE RINGGADE 1
8000 Aarhus C
Denmark
Region
Danmark Midtjylland Østjylland
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data