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P4SB – From Plastic waste to Plastic value using Pseudomonas putida Synthetic Biology

Objective

P4SB is about the utilization of the conceptual and material tools of contemporary Synthetic Biology to bring about the sustainable and environmentally friendly bioconversion of oil-based plastic waste into fully biodegradable counterparts by means of deeply engineered, whole-cell bacterial catalysts. These tools will be used to design tailor-made enzymes for the bio-depolymerization of PET (polyethylene terephthalate) and PU (polyurethane), but also for the custom design of a Pseudomonas putida Cell Factory capable of metabolizing the resulting monomers. Pseudomonas putida will undergo deep metabolic surgery to channel these diverse substrates efficiently into the production of polyhydroxyalkanoates (PHA) and derivatives. In addition, synthetic downstream processing modules based on the programmed non-lytic secretion of PHA will facilitate the release and recovery of the bioplastic from the bacterial biomass.

These industry driven objectives will help to address the market need for novel routes to valorise the gigantic plastic waste streams in the European Union and beyond, with direct opportunities for SME partners of P4SB spanning the entire value chain from plastic waste via Synthetic Biology to biodegradable plastic. As a result we anticipate a completely biobased process reducing the environmental impact of plastic waste by establishing it as a novel bulk second generation carbon source for industrial biotechnology, while at the same time opening new opportunities for the European plastic recycling industry and helping to achieve the ambitious recycling targets set by the European Union for 2020.
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Coordinator

RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN

Address

Templergraben 55
52062 Aachen

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 387 062,50

Participants (10)

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UNIVERSITAET LEIPZIG

Germany

EU Contribution

€ 981 875

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain

EU Contribution

€ 561 875

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

Ireland

EU Contribution

€ 540 625

BIOPLASTECH LTD

Ireland

EU Contribution

€ 628 781

BACMINE SL

Spain

EU Contribution

€ 684 625

HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ

Germany

EU Contribution

€ 488 625

UNIVERSITY OF SURREY

United Kingdom

EU Contribution

€ 628 125

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

EU Contribution

€ 524 375

SOPREMA

France

EU Contribution

€ 317 375

PROTEUS

France

EU Contribution

€ 313 625

Project information

Grant agreement ID: 633962

Status

Closed project

  • Start date

    1 April 2015

  • End date

    31 March 2019

Funded under:

H2020-EU.2.1.4.

  • Overall budget:

    € 7 056 968,75

  • EU contribution

    € 7 056 968,50

Coordinated by:

RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN

Germany

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