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P4SB – From Plastic waste to Plastic value using Pseudomonas putida Synthetic Biology

Objective

P4SB is about the utilization of the conceptual and material tools of contemporary Synthetic Biology to bring about the sustainable and environmentally friendly bioconversion of oil-based plastic waste into fully biodegradable counterparts by means of deeply engineered, whole-cell bacterial catalysts. These tools will be used to design tailor-made enzymes for the bio-depolymerization of PET (polyethylene terephthalate) and PU (polyurethane), but also for the custom design of a Pseudomonas putida Cell Factory capable of metabolizing the resulting monomers. Pseudomonas putida will undergo deep metabolic surgery to channel these diverse substrates efficiently into the production of polyhydroxyalkanoates (PHA) and derivatives. In addition, synthetic downstream processing modules based on the programmed non-lytic secretion of PHA will facilitate the release and recovery of the bioplastic from the bacterial biomass.

These industry driven objectives will help to address the market need for novel routes to valorise the gigantic plastic waste streams in the European Union and beyond, with direct opportunities for SME partners of P4SB spanning the entire value chain from plastic waste via Synthetic Biology to biodegradable plastic. As a result we anticipate a completely biobased process reducing the environmental impact of plastic waste by establishing it as a novel bulk second generation carbon source for industrial biotechnology, while at the same time opening new opportunities for the European plastic recycling industry and helping to achieve the ambitious recycling targets set by the European Union for 2020.

Call for proposal

H2020-LEIT-BIO-2014-1
See other projects for this call

Coordinator

RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN
Address
Templergraben 55
52062 Aachen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 387 062,50

Participants (10)

UNIVERSITAET LEIPZIG
Germany
EU contribution
€ 981 875
Address
Ritterstrasse 26
04109 Leipzig
Activity type
Higher or Secondary Education Establishments
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 561 875
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 540 625
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
BIOPLASTECH LTD
Ireland
EU contribution
€ 628 781
Address
Cashel Road Unit 9 Block C Cashel Business Centre
12 Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BACMINE SL
Spain
EU contribution
€ 684 625
Address
Calle Isaac Newton 2 Parque
28760 Tres Cantos
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ
Germany
EU contribution
€ 488 625
Address
Permoserstrasse 15
04318 Leipzig
Activity type
Other
UNIVERSITY OF SURREY
United Kingdom
EU contribution
€ 628 125
Address
Stag Hill
GU2 7XH Guildford
Activity type
Higher or Secondary Education Establishments
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 524 375
Address
Rue Michel Ange 3
75794 Paris
Activity type
Other
SOPREMA
France
EU contribution
€ 317 375
Address
14 Rue Saint Nazaire
67100 Strasbourg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PROTEUS
France
EU contribution
€ 313 625
Address
23 Rue Bossuet Zi De La Vigne Aux Loups
91160 Longjumeau
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)