Mechanisms of RNA-guided genome editing in eukaryotes

Project Information

G-EDIT

Grant agreement ID: 681178

DOI 10.3030/681178

Project closed

EC signature date 24 February 2016

Start date 1 May 2016

End date 30 April 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 953 000,00

EU contribution € 1 953 000,00

Coordinated by

UNIVERSITAET BERN
Switzerland

Publications

Peer reviewed articles (10)

A mating-type mutagenesis screen identifies a zinc-finger protein required for specific DNA excision events in Paramecium.

Author(s): Simran Bhullar; Simran Bhullar; Cyril Denby Wilkes; Olivier Arnaiz; Mariusz Nowacki; Linda Sperling; Eric Meyer
Published in: EISSN: 1362-4962, Issue 4, 2018, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.7892/boris.119691

Roles of Noncoding RNAs in Ciliate Genome Architecture

Author(s): Sarah E. Allen, Mariusz Nowacki
Published in: Journal of Molecular Biology, Issue 432/15, 2020, Page(s) 4186-4198, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2019.12.042

Necessity Is the Mother of Invention: Ciliates, Transposons, and Transgenerational Inheritance

Author(s): Sarah E. Allen, Mariusz Nowacki
Published in: Trends in Genetics, Issue 33/3, 2017, Page(s) 197-207, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/j.tig.2017.01.005

Determination of the presence of 5-methylcytosine in Paramecium tetraurelia.

Author(s): Aditi Singh; Adrienne Vancura; Rafal Woycicki; Daniel J. Hogan; Alan G. Hendrick; Mariusz Nowacki
Published in: PLoS ONE, Issue 1, 2018, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.7892/boris.120859

From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond

Author(s): Flavia Michelini, Ameya P. Jalihal, Sofia Francia, Chance Meers, Zachary T. Neeb, Francesca Rossiello, Ubaldo Gioia, Julio Aguado, Corey Jones-Weinert, Brian Luke, Giuseppe Biamonti, Mariusz Nowacki, Francesca Storici, Piero Carninci, Nils G. Walter, Fabrizio d’Adda di Fagagna
Published in: Chemical Reviews, Issue 118/8, 2018, Page(s) 4365-4403, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.7b00487

Identification and analysis of functional associations among natural eukaryotic genome editing components

Author(s): Estienne C. Swart, Cyril Denby Wilkes, Pamela Y. Sandoval, Cristina Hoehener, Aditi Singh, Dominique I. Furrer, Miroslav Arambasic, Michael Ignarski, Mariusz Nowacki
Published in: F1000Research, Issue 6, 2017, Page(s) 1374, ISSN 2046-1402
Publisher: F1000 Research Ltd.
DOI: 10.12688/f1000research.12121.1

Dicer-like Enzymes with Sequence Cleavage Preferences

Author(s): Cristina Hoehener, Iris Hug, Mariusz Nowacki
Published in: Cell, 2018, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2018.02.029

Two Sets of Piwi Proteins Are Involved in Distinct sRNA Pathways Leading to Elimination of Germline-Specific DNA

Author(s): Dominique I. Furrer, Estienne C. Swart, Matthias F. Kraft, Pamela Y. Sandoval, Mariusz Nowacki
Published in: Cell Reports, Issue 20/2, 2017, Page(s) 505-520, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2017.06.050

Circular Concatemers of Ultra-Short DNA Segments Produce Regulatory RNAs

Author(s): Allen, Sarah E.; Hug, Iris; Pabian, Sylwia; Rzeszutek, Iwona; Hoehener, Cristina; Nowacki, Mariusz
Published in: Cell, Issue 1, 2017, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.7892/boris.97052

Determination of the presence of 5-methylcytosine in Paramecium tetraurelia

Author(s): Aditi Singh, Adrienne Vancura, Rafal K. Woycicki, Daniel J. Hogan, Alan G. Hendrick, Mariusz Nowacki
Published in: PLOS ONE, Issue 13/10, 2018, Page(s) e0206667, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0206667