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How retrotransposons remodel the genome during early development and reprogramming

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Publications

The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s

Author(s): Hale Tunbak, Rocio Enriquez-Gasca, Christopher H. C. Tie, Poppy A. Gould, Petra Mlcochova, Ravindra K. Gupta, Liane Fernandes, James Holt, Annemarthe G. van der Veen, Evangelos Giampazolias, Kathleen H. Burns, Pierre V. Maillard, Helen M. Rowe
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-19170-5

KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control

Author(s): Christopher HC Tie, Liane Fernandes, Lucia Conde, Luisa Robbez‐Masson, Rebecca P Sumner, Tom Peacock, Maria Teresa Rodriguez‐Plata, Greta Mickute, Robert Gifford, Greg J Towers, Javier Herrero, Helen M Rowe
Published in: EMBO reports, Issue 19/10, 2018, Page(s) e45000, ISSN 1469-221X
DOI: 10.15252/embr.201745000

Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!

Author(s): Luisa Robbez-Masson, Christopher H.C. Tie, Helen M. Rowe
Published in: The Journal of Cell Biology, Issue 216/11, 2017, Page(s) 3429-3431, ISSN 0021-9525
DOI: 10.1083/jcb.201710068