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Regulation of DNA interstrand crosslink repair by ubiquitin.

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Publications

Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements

Author(s): Francesca E. Morreale, Andrea Testa, Viduth K. Chaugule, Alessio Bortoluzzi, Alessio Ciulli, Helen Walden
Published in: Journal of Medicinal Chemistry, Issue 60/19, 2017, Page(s) 8183-8191, ISSN 0022-2623
DOI: 10.1021/acs.jmedchem.7b01071

Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening

Author(s): Francesca E. Morreale, Alessio Bortoluzzi, Viduth K. Chaugule, Connor Arkinson, Helen Walden, Alessio Ciulli
Published in: Journal of Medicinal Chemistry, Issue 60/9, 2017, Page(s) 4093-4098, ISSN 0022-2623
DOI: 10.1021/acs.jmedchem.7b00147

Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1

Author(s): Connor Arkinson, Viduth K Chaugule, Rachel Toth, Helen Walden
Published in: Life Science Alliance, Issue 1/5, 2018, Page(s) e201800162, ISSN 2575-1077
DOI: 10.26508/lsa.201800162

Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins

Author(s): Viduth K. Chaugule, Connor Arkinson, Rachel Toth, Helen Walden
Published in: Ubiquitin and Ubiquitin-like Protein Modifiers, Issue 618, 2019, Page(s) 73-104
DOI: 10.1016/bs.mie.2018.12.021