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NMDA receptor diversity: from molecular dynamics to synaptic physiopathology


Architecture and function of NMDA receptors: an evolutionary perspective

Author(s): David Stroebel, Pierre Paoletti
Published in: The Journal of Physiology, 599/10, 2021, Page(s) 2615-2638, ISSN 0022-3751
Publisher: Blackwell Publishing Inc.
DOI: 10.1113/jp279028

Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice

Author(s): Wangyong Shin, Kyungdeok Kim, Benjamin Serraz, Yi Sul Cho, Doyoun Kim, Muwon Kang, Eun-Jae Lee, Hyejin Lee, Yong Chul Bae, Pierre Paoletti, Eunjoon Kim
Published in: PLOS Biology, 18/4, 2020, Page(s) e3000717, ISSN 1545-7885
Publisher: Public Library of Sciences
DOI: 10.1371/journal.pbio.3000717

Optocontrol of glutamate receptor activity by single side-chain photoisomerization

Author(s): Viktoria Klippenstein, Christian Hoppmann, Shixin Ye, Lei Wang, Pierre Paoletti
Published in: eLife, 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.25808

Probing Ion Channel Structure and Function Using Light-Sensitive Amino Acids

Author(s): Viktoria Klippenstein, Laetitia Mony, Pierre Paoletti
Published in: Trends in Biochemical Sciences, 43/6, 2018, Page(s) 436-451, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2018.02.012

Triheteromeric NMDA receptors: from structure to synaptic physiology

Author(s): David Stroebel, Mariano Casado, Pierre Paoletti
Published in: Current Opinion in Physiology, 2, 2018, Page(s) 1-12, ISSN 2468-8673
Publisher: Elsevier BV
DOI: 10.1016/j.cophys.2017.12.004

Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses

Author(s): Joana S Ferreira, Thomas Papouin, Laurent Ladépêche, Andrea Yao, Valentin C Langlais, Delphine Bouchet, Jérôme Dulong, Jean-Pierre Mothet, Silvia Sacchi, Loredano Pollegioni, Pierre Paoletti, Stéphane Henri Richard Oliet, Laurent Groc
Published in: eLife, 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.25492

An inter‐dimer allosteric switch controls NMDA receptor activity

Author(s): Jean‐Baptiste Esmenjaud, David Stroebel, Kelvin Chan, Teddy Grand, Mélissa David, Lonnie P Wollmuth, Antoine Taly, Pierre Paoletti
Published in: The EMBO Journal, 38/2, 2019, Page(s) e99894, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201899894

Unmasking GluN1/GluN3A excitatory glycine NMDA receptors

Author(s): Teddy Grand, Sarah Abi Gerges, Mélissa David, Marco A. Diana, Pierre Paoletti
Published in: Nature Communications, 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-07236-4

Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity

Author(s): Lulu Yao, Teddy Grand, Jesse E. Hanson, Pierre Paoletti, Qiang Zhou
Published in: Nature Communications, 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-06512-7

Optical control of neuronal ion channels and receptors

Author(s): Pierre Paoletti, Graham C. R. Ellis-Davies, Alexandre Mourot
Published in: Nature Reviews Neuroscience, 20/9, 2019, Page(s) 514-532, ISSN 1471-003X
Publisher: Nature Publishing Group
DOI: 10.1038/s41583-019-0197-2

Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula

Author(s): Y. Otsu, E. Darcq, K. Pietrajtis, F. Mátyás, E. Schwartz, T. Bessaih, S. Abi Gerges, C. V. Rousseau, T. Grand, S. Dieudonné, P. Paoletti, L. Acsády, C. Agulhon, B. L. Kieffer, M. A. Diana
Published in: Science, 366/6462, 2019, Page(s) 250-254, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aax1522

Synaptic zinc contributes to motor and cognitive deficits in 6-hydroxydopamine mouse models of Parkinson's disease

Author(s): Joanna Sikora, Brigitte L. Kieffer, Pierre Paoletti, Abdel-Mouttalib Ouagazzal
Published in: Neurobiology of Disease, 134, 2020, Page(s) 104681, ISSN 0969-9961
Publisher: Academic Press
DOI: 10.1016/j.nbd.2019.104681

Glycine agonism in ionotropic glutamate receptors

Author(s): David Stroebel, Laetitia Mony, Pierre Paoletti
Published in: Neuropharmacology, 193, 2021, Page(s) 108631, ISSN 0028-3908
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2021.108631

Photocontrol of Metabotropic Glutamate Receptors: When One Agonist Is Not Enough, Make It Two

Author(s): Laetitia Mony, Pierre Paoletti
Published in: Neuron, 105/3, 2020, Page(s) 395-397, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2020.01.013