Elucidating the role of m6A RNA methylation on the replication and pathogenesis of influenza A virus.

Project Information

IAV-m6A

Grant agreement ID: 747810

DOI 10.3030/747810

Project closed

EC signature date 3 April 2017

Start date 1 June 2017

End date 31 May 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 264 668,40

EU contribution € 264 668,40

Coordinated by

INSTITUT PASTEUR
France

Publications

Peer reviewed articles (5)

Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication

Author(s): David G. Courtney, Edward M. Kennedy, Rebekah E. Dumm, Hal P. Bogerd, Kevin Tsai, Nicholas S. Heaton, Bryan R. Cullen
Published in: Cell Host & Microbe, Issue 22/3, 2017, Page(s) 377-386.e5, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2017.08.004

Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication

Author(s): Kevin Tsai, David G. Courtney, Bryan R. Cullen
Published in: PLOS Pathogens, Issue 14/2, 2018, Page(s) e1006919, ISSN 1553-7374
Publisher: PLOS Pathogens
DOI: 10.1371/journal.ppat.1006919

Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication

Author(s): Kevin Tsai, David G. Courtney, Edward M. Kennedy, Bryan R. Cullen
Published in: RNA, 2018, Page(s) rna.066332.118, ISSN 1355-8382
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1261/rna.066332.118

Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression

Author(s): David G. Courtney, Andrea Chalem, Hal P. Bogerd, Brittany A. Law, Edward M. Kennedy, Christopher L. Holley, Bryan R. Cullen
Published in: mBio, Issue 10/3, 2019, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1128/mbio.01209-19

Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression

Author(s): David G. Courtney, Kevin Tsai, Hal P. Bogerd, Edward M. Kennedy, Brittany A. Law, Ann Emery, Ronald Swanstrom, Christopher L. Holley, Bryan R. Cullen
Published in: Cell Host & Microbe, Issue 26/2, 2019, Page(s) 217-227.e6, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2019.07.005