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European programme for the establishment of validated procedures for the detection and identification of biological toxins

European programme for the establishment of validated procedures for the detection and identification of biological toxins

Objective

Recent incidents in Europe and worldwide have threatened civil society by the attempted use of different biological toxins and have thereby shown that increased vigilance and adequate preparation is of increasing importance in a world facing growing risks of man-made disasters. Previous studies which the consortium is well acquainted with showed that there is a lack of robustness in European preparedness for biotoxin incidents. There is a need for standard analytical tools and procedures, reference materials, state-of-the-art training and establishment of a European proficiency testing scheme.

Using current best practice, the EuroBioTox core members will develop and validate improved analytical tools, reagents and standard operating procedures based on realistic incident scenarios. Certified Reference Materials for the threat biotoxins will be developed and, by establishing a European repository, will be made available to the EuroBioTox network including more than 50 European organisations, expert laboratories, industrial partners and end-users. Training courses at basic and advanced levels will be developed and attended by the EuroBioTox network partners, followed by a series of proficiency tests which, through these “outer circle” associates, will disseminate best practice methods across Europe. The current animal test for botulinum neurotoxin is ethically unacceptable and alternative in vitro tests will be evaluated.

After this project there will be a pan-European network of competence, certified reference materials, standard operating procedures and a common way of handling biotoxin incidents.

Coordinator

ROBERT KOCH-INSTITUT

Address

Nordufer 20
13353 Berlin

Germany

Activity type

Research Organisations

EU Contribution

€ 2 147 601,25

Participants (13)

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JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION

Belgium

EU Contribution

€ 807 760

INSTITUT SCIENTIFIQUE DE SANTE PUBLIQUE

Belgium

SCIENSANO

Belgium

EU Contribution

€ 453 825

HELSINGIN YLIOPISTO

Finland

EU Contribution

€ 512 691,25

INSTITUT PASTEUR

France

EU Contribution

€ 685 363,75

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

France

EU Contribution

€ 873 951,25

AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL

France

EU Contribution

€ 361 537,50

TOXOGEN GMBH

Germany

EU Contribution

€ 964 318,25

TOTALFORSVARETS FORSKNINGSINSTITUT

Sweden

EU Contribution

€ 896 346,25

EIDGENOSSISCHES DEPARTEMENT FUR VERTEIDIGUNG, BEVOLKERUNGSSCHUTZ UND SPORT

Switzerland

LUGINBUEHL WERNER

Switzerland

ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN

Switzerland

THE QUEEN'S UNIVERSITY OF BELFAST

United Kingdom

EU Contribution

€ 295 352,50

Project information

Grant agreement ID: 740189

Status

Ongoing project

  • Start date

    1 June 2017

  • End date

    31 May 2022

Funded under:

H2020-EU.3.7.1.

H2020-EU.3.7.5.

  • Overall budget:

    € 9 526 721,25

  • EU contribution

    € 7 998 747

Coordinated by:

ROBERT KOCH-INSTITUT

Germany