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Designer recombinases for efficient and safe genome surgery

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Publications

A single reporter mouse line for Vika, Flp, Dre, and Cre-recombination

Author(s): Madina Karimova, Oliver Baker, Aylin Camgoz, Ronald Naumann, Frank Buchholz, Konstantinos Anastassiadis
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-32802-7

Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors

Author(s): Duran Sürün, Aksana Schneider, Jovan Mircetic, Katrin Neumann, Felix Lansing, Maciej Paszkowski-Rogacz, Vanessa Hänchen, Min Ae Lee-Kirsch, Frank Buchholz
Published in: Genes, Issue 11/5, 2020, Page(s) 511, ISSN 2073-4425
DOI: 10.3390/genes11050511

A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus

Author(s): Felix Lansing, Maciej Paszkowski-Rogacz, Lukas Theo Schmitt, Paul Martin Schneider, Teresa Rojo Romanos, Jan Sonntag, Frank Buchholz
Published in: Nucleic Acids Research, Issue 48/1, 2019, Page(s) 472-485, ISSN 0305-1048
DOI: 10.1093/nar/gkz1078