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A new era in personalised medicine: Radiomics as decision support tool for diagnostics and theragnostics in oncology

Objective

The high degree of tumour (genomic and phenotypic) heterogeneity influences patient’s response to therapy and hampers wide deployment of personalised medicine for cancer treatment. Thus, there is an imperative need for new technologies that can accurately detect tumour heterogeneity, allow for patient stratification and assist clinicians in providing the right diagnosis and treatment for the right patient. PREDICT’s mission is to address this huge unmet need.
Radiomics, a newly emerging field that uses high-throughput extraction of large amounts of features from radiographic images, can boost the field of personalised medicine. The analysis of medical images taken as standard-of-care allows Radiomics to capture tumour heterogeneity and to generate ‘tumour-specific’ signatures in a non-invasive way, without the need of assessing the patient’s genetic profile. Thus, Radiomics, if linked to Big- data and decision support systems (DSS), can be used as diagnostic tool for patient stratification, for prediction of treatment response and for guidance, involving the patient, of clinical decisions in oncology. However, researchers that understand cancer biology, advanced imaging and big data analytics are virtually absent. Even more challenging is to translate the outcomes into actual clinical tools involving the patient.
PREDICT will train 15 highly promising researchers in the emerging field of Radiomics and Big data. These ESRs will be trained to implement the automatic exploitation of large amounts of imaging data to drive decision-making algorithms that will guide diagnosis and treatment of different types of cancer and to develop ‘tumour-specific’ signatures integrated in multifactorial DSS. The ESRs will become experts and innovators in Radiomics, Big Data and DSS, which will allow them to bring unique solutions towards the clinic. PREDICT builds upon a strong consortium with 8 academic and 10 non-academic partners that are all pioneers in their respective field.

Coordinator

UNIVERSITEIT MAASTRICHT
Net EU contribution
€ 510 748,56
Address
Minderbroedersberg 4
6200 MD Maastricht
Netherlands

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Region
Limburg (NL) Zuid-Limburg
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (9)

FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI
Italy
Net EU contribution
€ 386 876,93
Address
Via Venezian 1
20133 Milan

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Region
Nord-Ovest Lombardia Milano
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITE DE LIEGE
Belgium
Net EU contribution
€ 250 560,00
Address
Place Du 20 Aout 7
4000 Liege

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Region
Région wallonne Prov. Liège Arr. Liège
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Participation ended

Netherlands
Net EU contribution
€ 0,00
Address
Dr Molewaterplein 40
3015 GD Rotterdam

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Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
Net EU contribution
€ 498 432,96
Address
Im Neuenheimer Feld 280
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Non-EU contribution
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 525 751,20
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ONCORADIOMICS
Belgium
Net EU contribution
€ 501 120,00
Address
Clos Chanmurly 13
4000 Liege

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région wallonne Prov. Liège Arr. Liège
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
MIRADA MEDICAL LTD
United Kingdom
Net EU contribution
€ 273 287,88
Address
New Barclay House 234 Botley Road
OX2 0HP Oxford

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
PERSPECTUM LTD
United Kingdom
Net EU contribution
€ 273 287,88
Address
Gemini One, 5520 John Smith Drive Oxford Business Park South
OX4 2LL Oxford

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
HEALTH INNOVATION VENTURES BV
Netherlands
Net EU contribution
€ 368 873,96
Address
Oxfordlaan 55 Biopartner Gebouw
6229 EV Maastricht

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Limburg (NL) Zuid-Limburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00

Partners (8)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

EXOMNIS BIOTECH
Netherlands
Net EU contribution
€ 0,00
Address
Oxfordlaan 55
6229 EV Maastricht

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Region
Limburg (NL) Zuid-Limburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

ELSEVIER BV
Netherlands
Net EU contribution
€ 0,00
Address
Radarweg 29
1043NX Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

EUROPEAN CANCER PATIENT COALITION
Belgium
Net EU contribution
€ 0,00
Address
Avenue Des Arts 6
1210 Bruxelles

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Other
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

TTOPSTART BV
Netherlands
Net EU contribution
€ 0,00
Address
Laan Van Zuid Hoorn 15
2289 DC Rijswijk

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Region
West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Siemens
Germany
Net EU contribution
€ 0,00
Address

Munich

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Universita' Cattolica S. Cuore, Roma
Italy
Net EU contribution
€ 0,00
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UNIVERSITATSKLINIKUM HEIDELBERG
Germany
Net EU contribution
€ 0,00
Address
Im Neuenheimer Feld 672
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

HEIDELBERGER IONENSTRAHL THERAPIE (HIT) BETRIEBS GESELLSCHAFT AM UNIVERSITATSKLINIKUM HEIDELBERG MIT BESCHRANKTER HAFTUNG
Germany
Net EU contribution
€ 0,00
Address
Im Neuenheimer Feld 450
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00