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A new era in personalised medicine: Radiomics as decision support tool for diagnostics and theragnostics in oncology

Objective

The high degree of tumour (genomic and phenotypic) heterogeneity influences patient’s response to therapy and hampers wide deployment of personalised medicine for cancer treatment. Thus, there is an imperative need for new technologies that can accurately detect tumour heterogeneity, allow for patient stratification and assist clinicians in providing the right diagnosis and treatment for the right patient. PREDICT’s mission is to address this huge unmet need.
Radiomics, a newly emerging field that uses high-throughput extraction of large amounts of features from radiographic images, can boost the field of personalised medicine. The analysis of medical images taken as standard-of-care allows Radiomics to capture tumour heterogeneity and to generate ‘tumour-specific’ signatures in a non-invasive way, without the need of assessing the patient’s genetic profile. Thus, Radiomics, if linked to Big- data and decision support systems (DSS), can be used as diagnostic tool for patient stratification, for prediction of treatment response and for guidance, involving the patient, of clinical decisions in oncology. However, researchers that understand cancer biology, advanced imaging and big data analytics are virtually absent. Even more challenging is to translate the outcomes into actual clinical tools involving the patient.
PREDICT will train 15 highly promising researchers in the emerging field of Radiomics and Big data. These ESRs will be trained to implement the automatic exploitation of large amounts of imaging data to drive decision-making algorithms that will guide diagnosis and treatment of different types of cancer and to develop ‘tumour-specific’ signatures integrated in multifactorial DSS. The ESRs will become experts and innovators in Radiomics, Big Data and DSS, which will allow them to bring unique solutions towards the clinic. PREDICT builds upon a strong consortium with 8 academic and 10 non-academic partners that are all pioneers in their respective field.

Call for proposal

H2020-MSCA-ITN-2017
See other projects for this call

Coordinator

UNIVERSITEIT MAASTRICHT
Address
Minderbroedersberg 4
6200 MD Maastricht
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 510 748,56

Participants (9)

FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI
Italy
EU contribution
€ 386 876,93
Address
Via Venezian 1
20133 Milan
Activity type
Research Organisations
UNIVERSITE DE LIEGE
Belgium
EU contribution
€ 250 560
Address
Place Du 20 Aout 7
4000 Liege
Activity type
Higher or Secondary Education Establishments
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Participation ended

Netherlands
EU contribution
€ 0
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 498 432,96
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 525 751,20
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
ONCORADIOMICS
Belgium
EU contribution
€ 501 120
Address
Clos Chanmurly 13
4000 Liege
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MIRADA MEDICAL LTD
United Kingdom
EU contribution
€ 273 287,88
Address
New Road Ocfi
OX1 1BY Oxford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PERSPECTUM LTD
United Kingdom
EU contribution
€ 273 287,88
Address
Gemini One, 5520 John Smith Drive Oxford Business Park South
OX4 2LL Oxford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HEALTH INNOVATION VENTURES BV
Netherlands
EU contribution
€ 368 873,96
Address
Oxfordlaan 55 Biopartner Gebouw
6229 EV Maastricht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)

Partners (8)

EXOMNIS BIOTECH
Netherlands
Address
Oxfordlaan 55
6229 EV Maastricht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ELSEVIER BV
Netherlands
Address
Radarweg 29
1043NX Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EUROPEAN CANCER PATIENT COALITION
Belgium
Address
Rue Montoyer 40
1000 Bruxelles
Activity type
Other
TTOPSTART BV
Netherlands
Address
Euclideslaan 1
3584 BL Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Siemens
Germany
Address

Munich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Universita' Cattolica S. Cuore, Roma
Italy
Address

Roma
Activity type
Higher or Secondary Education Establishments
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
Address
Im Neuenheimer Feld 672
69120 Heidelberg
Activity type
Higher or Secondary Education Establishments
HEIDELBERGER IONENSTRAHL THERAPIE (HIT) BETRIEBS GESELLSCHAFT AM UNIVERSITATSKLINIKUM HEIDELBERG MIT BESCHRANKTER HAFTUNG
Germany
Address
Im Neuenheimer Feld 450
69120 Heidelberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)