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Veterinary Validation of Point-of-Care Detection Instrument

Objective

In the VIVALDI project the consortium will validate new equipment (the VETPOD platform) for rapid on-site detection of zoonotic pathogens in industrial food and animal production chains.
The coordinator Technical University of Denmark (DTU) has developed the VETPOD platform based on Loop mediated isothermal amplification (LAMP) technology and optical read-out to a user interface, with disposable plastic cartridges (Lab-on-Chip, LOC) that can be adapted to an infinite number of assays for almost all pathogens.
We have a portable LOC system with optical detection: a system with polymeric chip made by injection moulded with multiple (8-32) chambers suitable for rapid online or on site detection of pathogens. The polymer chip with multiple chambers is able to perform LAMP to detect different pathogens at species level from multiple (8-30) samples within 30-60 min.
We want to validate the VETPOD platform for three important zoonotic pathogens: Avian Influenza Virus (AIV) or Highly Pathogenic Avian Influenza Virus (HPAIV), Salmonella spp. and Campylobacter spp. For HPAIV this will include identification of H types (H5 and H7), for Salmonella the identification of the most important serovars S. Enteritidis, S. Typhimurium and S. Dublin, and for Campylobacter species identification of C. jejuni and C. coli.
The validation includes two stages:
1) Validation by national reference laboratories in DK, SE, IT and FR. Each NRL will involve 10 external labs for ring trials.
2) End-user validation at private labs (SMEs) in DE and IT.
The equipment provider will prepare a business plan for sale of the VETPOD system.
The private labs will prepare business plans for using the VETPOD platform for at site animal health detection as well as for online detection of zoonotic pathogens in food and animal production chains.

Field of science

  • /medical and health sciences/health sciences/infectious disease/RNA virus/influenza
  • /medical and health sciences/health sciences/epidemiology/zoonosis

Call for proposal

H2020-SFS-2017-1
See other projects for this call

Funding Scheme

IA - Innovation action

Coordinator

DANMARKS TEKNISKE UNIVERSITET
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Denmark
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 491 054,79

Participants (6)

STATENS VETERINAERMEDICINSKA ANSTALT
Sweden
EU contribution
€ 302 269,65
Address
Ulls Vaeg 2B
75189 Uppsala
Activity type
Research Organisations
AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL
France
EU contribution
€ 361 051,63
Address
14 Rue Pierre Et Marie Curie
94700 Maisons Alfort
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI PARMA
Italy
EU contribution
€ 160 558,34
Address
Via Universita 12
43100 Parma
Activity type
Higher or Secondary Education Establishments
ACEL SERVICE SRL
Italy
EU contribution
€ 161 253,75
Address
Langhirano (Pr) Via Fanti D'italia, 9/1 Cap 43013
43013 Langhirano Pr
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MARTIN FRETTLOH
Germany
EU contribution
€ 120 806,88
Address
Siegener Strasse 27-29
57080 Siegen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DNA DIAGNOSTIC A/S
Denmark
EU contribution
€ 321 822,80
Address
Voldbjergvej 14
8240 Risskov
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)