Objective
"This interdisciplinary project focuses on the development of unprecedented autonomous novel photoactive nanoscopic molecular machines that “blink” for fluorescence microscopy imaging with a resolution higher than the light scattering limit. Its use in super-resolution imaging will represent a major innovation in imaging, both conceptually and practically, overcoming many inherent constraints associated with current techniques. By applying steady-state and time-resolved spectroscopies, photo-induced electron transfer will be used in these autonomous [2]rotaxanes to modulate fluorescence, and studies down to the single-molecule level (based on Stochastic Optical Reconstruction Microscopy) will be undertaken to achieve a new localization microscopy method (""Ring-STORM"") adapted for living cells, without the need for overexpressing genetically encoded fluorescent proteins.
The project will be developed at leading French research institutes, Institut des Sciences Moléculaires (ISM) and Institut d'Optique (LP2N-IOGS) both at the CNRS/Univ. Bordeaux. The fellow, a specialist in synthetic organic and supramolecular chemistry from Spain, will receive via the project training in molecular photochemistry/photophysics and super-resolution fluorescence imaging, providing him the necessary skills to design, develop and study novel tailored-made functional supramolecular architectures with enhanced spectroscopic properties. For this, the project is organized in synergistic work packages to assure efficient coordination and management, career development and training, science development, communication and technology transfer by patenting the new super-resolution imaging methodology that Ring-STORM expects to develop. This will give him independence and professional maturity towards an independent research career. The experience of the fellow, the expertise of the research groups, the infrastructure and equipment will assure the fulfilment of the project objectives."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences physical chemistry photochemistry
- natural sciences physical sciences optics microscopy super resolution microscopy
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75794 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.