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EUROPEAN DEVELOPMENT OF BIONICS VESTIBULAR IMPLANT FOR BILATERAL VESTIBULAR DYSFUNCTION

EUROPEAN DEVELOPMENT OF BIONICS VESTIBULAR IMPLANT FOR BILATERAL VESTIBULAR DYSFUNCTION

Objective

Vertigo of vestibular origin has a global prevalence of 38% in the elderly and deserves special attention because
of the high risk of falls and permanent functional disability, and even death. This seriously handicaps their lives,
disabling them of doing routine daily activities, such as driving and even walking. The associated total costs are
around 60.000 million euros in Europe. It is estimated that at least 100 million people worldwide could benefit
from a vestibular implant as an effective solution to this disease. Restoring the function of the vestibular
labyrinths was not possible until now. Current devices, under research, detect change in angular velocity of the
cephalic movements through gyroscopes and use this information to stimulate the semicircular canals. However,
they do not code vertical and horizontal accelerations, used to sense gravitational forces, keep a stand up position
and restore the sense of self-position. Linear accelerations are detected by a different set of structures which are a
more complex and harder to access: the saccule and utricle. This project will develop the first system to
electrically reproduce linear accelerations in the otolith organ by stimulating their neural ends. The project will
have three phases: Device design, fabrication and clinical trial. Therefore, the objectives will be: 1) to study, for
the first time, vestibular pathways through electrical saccule-utricle stimulation; 2) to develop a vestibular
response telemetry system to analyse the evoked action potential of vestibular nerve; 3) to design, manufacture
and test the first vestibular prosthesis that restores the sense of linear accelerations. The main objectives are to
demonstrate the safety of a vestibular implant for human, to determine its efficacy in restoring vestibular function
by measuring the improvement in objective and to objectify the improvement in Quality of Life of patients.

Coordinator

SERVICIO CANARIO DE LA SALUD

Address

PÉRez De Rozas, 5, 4 Planta
38006 Santa Cruz De Tenerife

Spain

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 655 442,50

Participants (5)

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UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA

Spain

EU Contribution

€ 297 620

UNIVERSIDAD DE NAVARRA

Spain

EU Contribution

€ 454 886,25

DIENST NEUS-KEEL-OOR SINT-AUGUSTINUS ANTWERPEN

Belgium

EU Contribution

€ 389 542,50

UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA

Italy

EU Contribution

€ 291 198,75

COCHLEAR RESEARCH AND DEVELOPMENT LIMITED

United Kingdom

EU Contribution

€ 811 000

Project information

Grant agreement ID: 801127

Status

Ongoing project

  • Start date

    1 September 2018

  • End date

    31 August 2022

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 2 899 690

  • EU contribution

    € 2 899 690

Coordinated by:

SERVICIO CANARIO DE LA SALUD

Spain