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EUROPEAN DEVELOPMENT OF BIONICS VESTIBULAR IMPLANT FOR BILATERAL VESTIBULAR DYSFUNCTION

Objective

Vertigo of vestibular origin has a global prevalence of 38% in the elderly and deserves special attention because
of the high risk of falls and permanent functional disability, and even death. This seriously handicaps their lives,
disabling them of doing routine daily activities, such as driving and even walking. The associated total costs are
around 60.000 million euros in Europe. It is estimated that at least 100 million people worldwide could benefit
from a vestibular implant as an effective solution to this disease. Restoring the function of the vestibular
labyrinths was not possible until now. Current devices, under research, detect change in angular velocity of the
cephalic movements through gyroscopes and use this information to stimulate the semicircular canals. However,
they do not code vertical and horizontal accelerations, used to sense gravitational forces, keep a stand up position
and restore the sense of self-position. Linear accelerations are detected by a different set of structures which are a
more complex and harder to access: the saccule and utricle. This project will develop the first system to
electrically reproduce linear accelerations in the otolith organ by stimulating their neural ends. The project will
have three phases: Device design, fabrication and clinical trial. Therefore, the objectives will be: 1) to study, for
the first time, vestibular pathways through electrical saccule-utricle stimulation; 2) to develop a vestibular
response telemetry system to analyse the evoked action potential of vestibular nerve; 3) to design, manufacture
and test the first vestibular prosthesis that restores the sense of linear accelerations. The main objectives are to
demonstrate the safety of a vestibular implant for human, to determine its efficacy in restoring vestibular function
by measuring the improvement in objective and to objectify the improvement in Quality of Life of patients.

Call for proposal

H2020-FETOPEN-2016-2017

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Sub call

H2020-FETOPEN-1-2016-2017

Coordinator

SERVICIO CANARIO DE LA SALUD
Net EU contribution
€ 728 544,74
Address
Pérez De Rozas, 5, 4 Planta
38006 Santa Cruz De Tenerife
Spain

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Region
Canarias Canarias Tenerife
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (6)

UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA
Spain
Net EU contribution
€ 297 620,00
Address
C/ Juan De Quesada 30
35001 Las Palmas De Gran Canaria

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Region
Canarias Canarias Gran Canaria
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSIDAD DE NAVARRA
Spain
Net EU contribution
€ 510 531,76
Address
Campus Universitario Edificio Central
31080 Pamplona

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Region
Noreste Comunidad Foral de Navarra Navarra
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
DIENST NEUS-KEEL-OOR SINT-AUGUSTINUS ANTWERPEN
Belgium
Net EU contribution
€ 383 704,45
Address
Oosterveldlaan 24
2610 Antwerpen

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Antwerpen Arr. Antwerpen
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA
Italy
Net EU contribution
€ 168 289,05
Address
Piazzale Aldo Moro 5
00185 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
COCHLEAR RESEARCH AND DEVELOPMENT LIMITED
United Kingdom
Net EU contribution
€ 811 000,00
Address
Dashwood Lang 6
KT15 2HJ Addlestone Surrey

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Region
South East (England) Surrey, East and West Sussex West Surrey
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
International partner

Legal entity established in a non-associated third country that is not eligible for funding under Article 10 of the Regulation (EU) No 1290/2013 laying down the rules for participation and dissemination in Horizon 2020.

Cochlear Limited

Not active in the Specific Grant Agreement of the project

Australia
Address
1 University Avenue
NSW 2019 Macquarie University

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)