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Quantitative detection of bacterial endotoxin by novel nanotechnological approaches

Project description

Innovative endotoxin detection using nanotechnology

Safety regulations require the unbiased quantitative detection of bacterial endotoxins in the products intended for medical use and drug development. The current Limulus amoebocyte lysate (LAL) assays have reliability limitations and cannot be applied to all products and substances. Funded by the Marie Skłodowska-Curie Actions programme, the ENDONANO project will exploit a novel concept based on the capacity of metal nanoparticles to adsorb endotoxins as well as detection methods based on molecular beacons. The aim is to develop an endotoxin quantitation assay that works in complex matrices and a wide range of conditions. ENDONANO will train four PhD researchers, providing courses in scientific, technical and transferrable skills, participation in scientific events, and networking.

Coordinator

CONSIGLIO NAZIONALE DELLE RICERCHE
Net EU contribution
€ 261 499,68
Address
Piazzale Aldo Moro 7
00185 Roma
Italy

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Other funding
€ 0,00

Participants (6)

PARIS-LODRON-UNIVERSITAT SALZBURG
Austria
Net EU contribution
€ 132 103,62
Address
Kapitelgasse 4-6
5020 Salzburg

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Region
Westösterreich Salzburg Salzburg und Umgebung
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA
Spain
Net EU contribution
€ 90 604,54
Address
Campus De La Uab Edifici Q Icn2
08193 Bellaterra (Barcelona)

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00
DIAGNOSTICUM GYARTO ES FORGALMAZO ZARTKORUEN MUKODO RESZVENYTARSASAG
Hungary
Net EU contribution
€ 114 857,64
Address
Attila U 126
1047 Budapest

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Közép-Magyarország Budapest Budapest
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
MILTENYI BIOTEC GMBH

Participation ended

Germany
Net EU contribution
€ 0,00
Address
Friedrich Ebert Strasse 68
51429 Bergish Gladbach
Region
Nordrhein-Westfalen Köln Rheinisch-Bergischer Kreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
BLUSENSE DIAGNOSTICS APS
Denmark
Net EU contribution
€ 148 761,00
Address
Fruebjergvej 3
2100 Kobenhavn

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Danmark Hovedstaden Byen København
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
MILTENYI BIOTEC BV & CO KG
Germany
Net EU contribution
€ 287 897,90
Address
Friedrich Ebert Strasse 68
51429 Bergisch Gladbach

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Region
Nordrhein-Westfalen Köln Rheinisch-Bergischer Kreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Partners (2)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

APPLIED NANOPARTICLES SL
Spain
Net EU contribution
€ 0,00
Address
Calle Alaba 88
08018 Barcelona

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

ALTA RICERCA E SVILUPPO IN BIOTECNOLOGIE SRLU
Italy
Net EU contribution
€ 0,00
Address
Via Fiorentina 151
53100 Siena

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centro (IT) Toscana Siena
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00