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Fostering Synthetic Biology standardisation through international collaboration

Objective

Synthetic Biology is an engineering research field aiming at (re)designing biological circuits for applied purposes. As any other engineering field, it strongly relies on the use of well-defined, universal and robust standard components. The outstanding success of synthetic biology in the last years should not hide the difficulties in defining biological standards. There are both historical and technical difficulties to reach that ambitious goal. On the former: the crossroad nature of synthetic biology involving mainly biologists/biotechnologists and engineers, whose views on the
standardisation of living beings tend to differ; among the latter: the intrinsic features of live (mutation, emergent properties, fitness biasses, variability and, of course, evolution). In BIOROBOOST we propose to finally overcome cultural issues and to dramatically advance in solving technical difficulties by i) gathering the most relevant stakeholders of all the aspects of standardisation in biology in Europe in a co-creation scenario; ii) by empirically testing cultural (lab-centric) standardisation practices and by promoting a consensus conceptual and technical redefinition
of biological standards; and, finally, iii) by fostering a realistic and flexible toolbox of standard biological parts, including a reduced set of specialised chassis for specific applications as well as a renewed conceptual framework to inform policy makers, scientific and other societal actors.
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Coordinator

UNIVERSITAT DE VALENCIA

Address

Avenida Blasco Ibanez 13
46010 Valencia

Spain

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 518 275

Participants (24)

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BIOFACTION KG

Austria

EU Contribution

€ 101 792,50

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 62 875

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain

EU Contribution

€ 104 292,50

DARWIN BIOPROSPECTING EXCELLENCE SOCIEDAD LIMITADA

Spain

EU Contribution

€ 123 225

DANMARKS TEKNISKE UNIVERSITET

Denmark

EU Contribution

€ 65 343,75

THE UNIVERSITY OF EDINBURGH

United Kingdom

EU Contribution

€ 133 250

EUROPEAN MOLECULAR BIOLOGY ORGANIZATION

Switzerland

EU Contribution

€ 62 000

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH

Switzerland

EU Contribution

€ 56 300

EXPLORA SRL

Italy

EU Contribution

€ 58 250

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

France

EU Contribution

€ 63 250

UNIVERSITEIT GENT

Belgium

EU Contribution

€ 64 475

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

EU Contribution

€ 102 300

KEMIJSKI INSTITUT

Slovenia

EU Contribution

€ 63 250

PHILIPPS UNIVERSITAET MARBURG

Germany

EU Contribution

€ 35 125

UNIVERSITY OF NEWCASTLE UPON TYNE

United Kingdom

EU Contribution

€ 60 750

PANEPISTIMIO THESSALIAS

Greece

EU Contribution

€ 63 875

UNIVERSITETET I OSLO

Norway

EU Contribution

€ 108 250

ASOCIACION ESPANOLA DE NORMALIZACION

Spain

EU Contribution

€ 59 250

THE UNIVERSITY OF WARWICK

United Kingdom

EU Contribution

€ 61 125

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

EU Contribution

€ 31 533,75

TSINGHUA UNIVERSITY

China

GINKGO BIOWORKS INC.

United States

WASEDA UNIVERSITY

Japan

NATIONAL UNIVERSITY OF SINGAPORE PUBLIC COMPANY LIMITED BY GUARANTEE

Singapore

Project information

Grant agreement ID: 820699

Status

Ongoing project

  • Start date

    1 October 2018

  • End date

    30 September 2021

Funded under:

H2020-EU.2.1.4.

  • Overall budget:

    € 2 177 587,50

  • EU contribution

    € 1 998 787,50

Coordinated by:

UNIVERSITAT DE VALENCIA

Spain