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Noninvasive cell specific morphometry in neuroinflammation and degeneration

Publications

Time-dependent and anisotropic diffusion in the heart: linear and spherical tensor encoding with varying degree of motion compensation

Author(s): Samo Lasic, Henrik Lundell, Filip Szczepankiewicz, Markus Nilsson, Jürgen E. Schneider, and Irvin Teh
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 28, 2020, Page(s) 4300
Publisher: ISMRM

Serum and cerebrospinal fluid neurofilament levels predict longitudinal atrophy of the cervical spinal cord in progressive MS

Author(s): Henrik Lundell, Jeppe Romme Christensen, Lars Börnsen, Cecilie Ammitzbøll, Helle Bach Søndergaard, Poul Erik Hyldgaard Jensen, Per Soelberg Sørensen, Ellen Garde, Finn Sellebjerg, Hartwig Roman Siebner
Published in: ECTRIMS, Issue 2019, 2019, Page(s) 906
Publisher: ECTRIMS

Micro-Anisotropy And Time-Dependent Diffusion In The Mouse Brain In Vivo With Spherical Tensor Encoding And The Spectral Principal Axis System

Author(s): Samo Lasic, Nathalie Just, Matthew Budde, Henrik Lundell
Published in: proc. intl. soc. mag. reson. med., Issue 31, 2023, Page(s) 5021
Publisher: ISMRM

Stay on the beat: tuning in on time-dependent diffusion inthe heart

Author(s): Henrik Lundell, Samo Lasic, Filip Szczepankiewicz, Markus Nilsson, Daniel Topgaard, Jürgen E. Schneider, Irvin Teh
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 28, 2020, Page(s) 959
Publisher: ISMRM

Time-Dependence In Tensor-Valued Encoding In Ex Vivo Rat Heart

Author(s): Richard J. Foster, Samo Lasič, Henrik Lundell, Filip Szczepankiewicz, Leah Khazin, Sven Plein, Erica Dall'Armellina, Nadira Y. Yuldasheva, Jürgen E. Schneider, Irvin Teh
Published in: proc. intl. soc. mag. reson. med., Issue 31, 2023, Page(s) 5010
Publisher: ISMRM

Investigating time dependent diffusion, microscopicanisotropy and T2 effects in the mouse heart

Author(s): Henrik Lundell, Samo Lasic, Filip Szczepankiewicz, Beata Wereszczyńska, Matthew Budde, Erica Dall'Armellina, Nadira Yuldasheva6, Jürgen E. Schneider, and Irvin Teh
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 2470
Publisher: ISMRM

Feasibility of cervical spinal cord cross-sectionalmeasurements from 3D T1w sagittal head MRI at 7T

Author(s): Vanessa Wiggermann, Henrik Lundell, Mads Alexander Just Madsen, Christopher Fugl Madelung, Hartwig Roman Siebner
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 3448
Publisher: ISMRM

Multidimensional Diffusion MRI Assists Myelin-sensitiveBound Pool Fraction in Differentiating MicrostructuralMaturity of Primate Brains

Author(s): Yi He, Henrik Lundell, Ines Mexia Rodrigues, Matthew D. Budde, Mark D. Does, Maurice Ptito, Tim Bjørn Dyrby
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 28, 2020, Page(s) 861
Publisher: ISMRM

Preliminary Evaluation Of Brain Neural Networks Following Chemogenetically-Induced Activation Of The Motor Cortex In Rats

Author(s): Mathias Lysholt Mathiasen, Sascha Gude, Henrik Lundell, Hartwig Roman Siebner, Nathalie Just
Published in: proc. intl. soc. mag. reson. med., Issue 31, 2023, Page(s) 3503
Publisher: ISMRM

Metabolite diffusion weighted imaging with golden angle radial echo planar spectroscopic imaging

Author(s): Vincent Oltman Boer, Itamar Ronen, Jan Ole Pedersen, Esben Thade Petersen, Henrik Lundell
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 27, 2019, Page(s) 3616
Publisher: ISMRM

Probing complex morphologies at decreasing diffusion times using Diffusion-weighted MR Spectroscopy

Author(s): Just, Nathalie; Lasic, Samo; Bentsen Christensen, Ditte; Valette, Julien; Dyrby, Tim; Siebner, Hartwig; Lundell, Henrik
Published in: proc. intl. soc. mag. reson. med., Issue 30, 2022, Page(s) 980
Publisher: ISMRM

Single-shot isotropic diffusion-weighted NMR spectroscopyin the human brain at 7T using tetrahedral encoding

Author(s): Chloé Najac, Henrik Lundell, Hermien E. Kan, Andrew G. Webb, Itamar Ronen
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 28, 2020, Page(s) 739
Publisher: ISMRM

The spectral tilt plot (STP) – new microstructuresignatures from spectrally anisotropic b-tensorencoding

Author(s): Samo Lasic, Filip Szczepankiewicz, Markus Nilsson, Tim B. Dyrby, Henrik Lundell
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 297
Publisher: ISMRM

Susceptibility-induced fiber orientation dependency ofthe DWI signal in white matter measured in ex vivorat brain at 7 T

Author(s): Sidsel Winther, Mariam Andersson, Henrik Lundell, Tim Dyrby
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 2041
Publisher: ISMRM

Tissue microstructure by ellipsoidal tensor encodingwith independently varying spectral anisotropy andtuning

Author(s): Samo Lasic, Henrik Lundell
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 2459
Publisher: ISMRM

Identification of ’black hole’ T1 hypointense lesions using different intensity thresholds on gradient-echo T1w MRI

Author(s): Wiggermann, Vanessa; Arnau Martinez, Mie; Merhout, Jasmin; Romme Christensen, Jeppe; Blinkenberg, Morten; Sellebjerg, Finn; Lundell, Henrik; Siebner, Hartwig
Published in: proc. intl. soc. mag. reson. med, Issue 30, 2022, Page(s) 783
Publisher: ISMRM

Susceptibility-induced B-field inhomogeneity of undulating axons and effects on the DWI signal

Author(s): Winther, Sidsel; Lundell, Henrik; Dyrby, Tim
Published in: proc. intl. soc. mag. reson. med., Issue 30, 2022, Page(s) 1045
Publisher: ISMRM

Time-dependent anisotropic diffusion in the mouse heart: feasibility of motion compensated tensor-valued encoding on a 7T preclinical scanner

Author(s): Samo Lasic, Henrik Lundell, Beata Wereszczyńska, Matthew Budde, Nadira Yuldasheva, Filip Szczepankiewicz, Erica Dall’Armellina, Jürgen E. Schneider, Irvin Teh
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 3651
Publisher: ISMRM

Reducing spectral anisotropy in isotropic b-tensor multidimensional diffusion encoding

Author(s): Henrik Lundell, Markus Nilsson, Filip Szczepankiewicz, Carl-Fredrik Westin, Daniel Topgaard, Samo Lasic
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 27, 2019, Page(s) 3503
Publisher: ISMRM

Data-driven separation of MRI signal components fortissue characterization

Author(s): Sofie Rahbek, Kristoffer H. Madsen, Henrik Lundell, Faisal Mahmood, and Lars G. Hanson
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 2471
Publisher: ISMRM

Feasibility of axon diameter estimation in complex fiber architectures by powder averaging of the diffusion MRI signal

Author(s): Mariam Andersson, Marco Pizzolato, Hans Martin Kjer, Henrik Lundell, Tim B. Dyrby
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 645
Publisher: ISMRM

A minimal geometrical model for Monte Carlo simulations of time dependent di!usion in axons

Author(s): Henrik Lundell, Samo Lasic
Published in: Proc. Intl. Soc. Mag. Reson. Mag., Issue 29, 2021, Page(s) 3403
Publisher: ISMRM

Time-Dependent Diffusion In The Human Heart In Vivo

Author(s): Irvin Teh, Sam Coveney, Richard J. Foster, Filip Szczepankiewicz, Samo Lasič, Henrik Lundell, David Shelley, Lars Mueller, Maryam Afzali, Noor Sharrack, Nadira Y. Yuldasheva, Sven Plein, Erica Dall'Armellina, and Jürgen E. Schneider
Published in: proc. intl. soc. mag. reson. med., Issue 31, 2023, Page(s) 344
Publisher: ISMRM

Differences in diffusion-weighted MRS processing and fitting pipelines, and their effect on tissue modeling: Results from a workshop challenge.

Author(s): Najac, Chloé; Döring, André; Clarke, William, Genovese, Guglielmo; Just, Nathalie; Kreis, Roland; Lundell, Henrik; Mosso, Jessie; Mougel, Eloïse; Oeltzschner, Georg; Palombo, Marco; Ligneul, Clémence
Published in: proc. intl. soc. mag. reson. med, Issue 30, 2022, Page(s) 2616
Publisher: ISMRM

Estimating compartment- and cell-specific microscopic anisotropy in the human brain using double-diffusion encoding spectroscopy at 7T

Author(s): Chloé Najac, Henrik Lundell, Marjolein Bulk, Hermien E. Kan, Andrew G. Webb, Itamar Ronen
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 27, 2019, Page(s) 56
Publisher: ISMRM

Spectral principal axes system (SPAS) and tuning of tensor-valued encoding for time-dependent anisotropic diffusion

Author(s): Lasic, Samo; Just, Nathalie; Lundell, Henrik
Published in: proc. intl. soc. mag. reson. med., Issue 30, 2022, Page(s) 2509
Publisher: ISMRM

Orientation-dependent biases in powder averaging causedby inhomogeneous distributions of magnetic susceptibilityin white matter

Author(s): Sidsel Winther, Henrik Lundell, Mariam Andersson, Tim Dyrby
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 28, 2020, Page(s) 734
Publisher: ISMRM

The tuned trinity of b-tensors

Author(s): Samo Lasic, Henrik Lundell, Daniel Topgaard
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 27, 2019, Page(s) 3490
Publisher: ISMRM

Multidimensional Diffusion MRI in the Ex Vivo MouseHeart

Author(s): Irvin Teh, Samo Lasic, Henrik Lundell, Beata Wereszczyńska, Matthew Budde, Erica Dall'Armellina, Nadira Yuldasheva, Filip Szczepankiewicz, and Jürgen E. Schneider
Published in: Proc. Intl. Soc. Mag. Reson. Med., Issue 29, 2021, Page(s) 3618
Publisher: ISMRM

Relationship between cerebrospinal fluid biomarkers of inflammation and tissue damage in primary progressive multiple sclerosis

Author(s): Jacob Talbot; Helene Højsgaard Chow; Mie Mahler; Sophie Buhelt; Rikke Holm Hansen; Henrik Lundell; Tua Vinther-Jensen; Marie N.N. Hellem; Jørgen E. Nielsen; Hartwig Roman Siebner; Marina R. von Essen; Finn Sellebjerg
Published in: Talbot , J , Højsgaard Chow , H , Mahler , M , Buhelt , S , Holm Hansen , R , Lundell , H , Vinther-Jensen , T , Hellem , M N N , Nielsen , J E , Siebner , H R , von Essen , M R & Sellebjerg , F 2022 , ' Relationship between cerebrospinal fluid biomarkers of inflammation and tissue damage in primary progressive multiple sclerosis ' , Multiple Sclerosis and Related Disorders , vol. 68 , 104209 . h, Issue 1, 2022, ISSN 2211-0348
Publisher: Elsevier
DOI: 10.1016/j.msard.2022.104209

Intrathecal CD8+CD20+ T Cells in Primary Progressive Multiple Sclerosis

Author(s): Marina Rode von Essen, Jacob Talbot, Rikke Holm Holm Hansen, Helene Højsgaard Chow, Henrik Lundell, Hartwig Roman Siebner, Finn Sellebjerg
Published in: Neurol Neuroimmunol Neuroinflamm, Issue 10 (5), 2023, Page(s) e200140, ISSN 2332-7812
Publisher: American Academy of Neurology
DOI: 10.1212/nxi.0000000000200140

An open-source tool for longitudinal whole-brain and white matter lesion segmentation

Author(s): Stefano Cerri, Douglas N Greve, Andrew Hoopes, Henrik Lundell, Hartwig R Siebner, Mark Mühlau, Koen Van Leemput
Published in: NeuroImage:Clinical, Issue 38, 2023, Page(s) 103354, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2023.103354

Dimethyl Fumarate Treatment in Patients With Primary Progressive Multiple Sclerosis

Author(s): Helene Højsgaard Chow, Jacob Talbot, Henrik Lundell, Camilla Gøbel Madsen, Lisbet Marstrand, Theis Lange, Mie Reith Mahler, Sophie Buhelt, Rikke Holm Hansen, Morten Blinkenberg, Jeppe Romme Christensen, Per Soelberg Sørensen, Marina Rode von Essen, Hartwig Roman Siebner, Finn Sellebjerg
Published in: Neurology - Neuroimmunology Neuroinflammation, Issue 8/5, 2021, Page(s) e1037, ISSN 2332-7812
Publisher: Wolters Kluwer Health
DOI: 10.1212/nxi.0000000000001037

Smoking, cardiovascular risk factors and LRP2 gene variation: Associations with disease severity, cognitive function and brain structure in primary progressive multiple sclerosis

Author(s): Helene Højsgaard Chow, Jacob Talbot, Lisbet Marstrand, Henrik Lundell, Hartwig Roman Siebner, Helle Bach Søndergaard, Finn Sellebjerg
Published in: Multiple Sclerosis and Related Disorders, Issue 56, 2021, Page(s) 103296, ISSN 2211-0348
Publisher: Elsevier
DOI: 10.1016/j.msard.2021.103296

Data-driven separation of MRI signal components for tissue characterization

Author(s): Sofie Rahbek, Kristoffer H. Madsen, Henrik Lundell, Faisal Mahmood, Lars G. Hanson
Published in: Journal of Magnetic Resonance, Issue 333, 2021, Page(s) 107103, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2021.107103

Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?

Author(s): Mariam Andersson, Marco Pizzolato, Hans Martin Kjer, Katrine Forum Skodborg, Henrik Lundell, Tim B. Dyrby
Published in: NeuroImage, Issue 333, 2021, Page(s) 118718, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2021.118718

Stay on the Beat With Tensor-Valued Encoding: Time-Dependent Diffusion and Cell Size Estimation in ex vivo Heart

Author(s): Samo Lasič; Nadira Yuldasheva; Filip Szczepankiewicz; Markus Nilsson; Matthew Budde; Erica Dall’Armellina; Jürgen E. Schneider; Irvin Teh; Henrik Lundell
Published in: Front. Phys., Issue 1, 2022, ISSN 2296-424X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fphy.2022.812115

Dimethyl fumarate treatment of primary progressive multiple sclerosis: results of an open-label extension study

Author(s): Helene Højsgaard Chow, Jacob Talbot, Henrik Lundell, Lisbet Marstrand, Camilla Gøbel Madsen, Helle Bach Søndergaard, Malene Bredahl Hansen, Per Solberg Sørensen, Hartwig Roman Siebner, Finn Sellebjerg
Published in: Multiple Sclerosis and Related Disorders, Issue 70, 2023, Page(s) 104458, ISSN 2211-0348
Publisher: Elsevier
DOI: 10.1016/j.msard.2022.104458

Multidimensional diffusion MRI with spectrally modulated gradients reveals unprecedented microstructural detail

Author(s): H. Lundell, M. Nilsson, T. B. Dyrby, G. J. M. Parker, P. L. Hubbard Cristinacce, F.-L. Zhou, D. Topgaard, S. Lasič
Published in: Scientific Reports, Issue 9/1, 2019, Page(s) 1-12, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-45235-7

Cytosolic diffusivity and microscopic anisotropy of N -acetyl aspartate in human white matter with diffusion-weighted MRS at 7 T

Author(s): Henrik Lundell, Carson Ingo, Tim B. Dyrby, Itamar Ronen
Published in: NMR in Biomedicine, 2020, Page(s) e4304, ISSN 0952-3480
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/nbm.4304

Cortical and Subcortical Effects of Transcutaneous Spinal Cord Stimulation in Humans with Tetraplegia

Author(s): Francisco D. Benavides, Hang Jin Jo, Henrik Lundell, V. Reggie Edgerton, Yuri Gerasimenko, Monica A. Perez
Published in: The Journal of Neuroscience, Issue 40/13, 2020, Page(s) 2633-2643, ISSN 0270-6474
Publisher: Society for Neuroscience
DOI: 10.1523/jneurosci.2374-19.2020

Compartmental diffusion and microstructural properties of human brain gray and white matter studied with double diffusion encoding magnetic resonance spectroscopy of metabolites and water

Author(s): Henrik Lundell, Chloé Najac, Marjolein Bulk, Hermien E. Kan, Andrew G. Webb, Itamar Ronen
Published in: NeuroImage, Issue 234, 2021, Page(s) 117981, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2021.117981

Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study

Author(s): Mads A J Madsen, Vanessa Wiggermann, Marta F M Marques, Henrik Lundell, Stefano Cerri, Oula Puonti, Morten Blinkenberg, Jeppe Romme Christensen, Finn Sellebjerg, Hartwig R Siebner
Published in: Brain, Issue 145, 2022, Page(s) 3522-3535, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awac203

Double diffusion encoding and applications for biomedical imaging

Author(s): Rafael N. Henriques, Marco Palombo, Sune N. Jespersen, Noam Shemesh, Henrik Lundell, Andrada Ianuş
Published in: Journal of Neuroscience Methods, Issue 348, 2021, Page(s) 108989, ISSN 0165-0270
Publisher: Elsevier BV
DOI: 10.1016/j.jneumeth.2020.108989

Chapter 2. Diffusion Encoding with General Gradient Waveforms

Author(s): Henrik Lundell, Samo Lasic
Published in: Advanced Diffusion Encoding Methods in MRI, 2020, Page(s) 12-67, ISBN 978-1-78801-726-8
Publisher: Royal Society of Chemistry
DOI: 10.1039/9781788019910-00012

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