Project description
Novel biomarkers for stratifying patients with primary Sjögren’s syndrome
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease (AID) presenting with heterogeneous clinical manifestations and biological disturbances. It primarily affects exocrine glands leading to dryness of the eyes and the mouth, but it can also cause kidney or lung disease. The multi-organ impact of pSS has hampered drug discovery with only one licensed drug in the last 20 years. Scientists of the EU-funded NECESSITY project will assist in drug-discovery efforts by determining sensitive clinical endpoints, for use in future clinical trials involving patients with pSS. Through a clinical trial, they will evaluate these endpoints alongside discriminative biomarkers for the stratification of patients with pSS.
Fields of science
Programme(s)
Funding Scheme
IMI2-RIA - Research and Innovation action
Coordinator
75654 Paris
France
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Participants (28)
Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
91190 Gif-sur-yvette
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B15 2TT Birmingham
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17177 Stockholm
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NE1 7RU Newcastle Upon Tyne
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67091 Strasbourg Cedex
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3584 CX Utrecht
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29238 Brest
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
29609 Brest
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41092 Sevilla
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10561 Athina
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75006 Paris
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75000 Paris
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75013 Paris
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
T12 YN60 Cork
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Participation ended
5020 Bergen
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00196 Roma
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
75018 Paris
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E1 4NS London
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33100 Udine
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75724 Paris Cedex 15
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4011 Stavanger
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9713 GZ Groningen
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08036 Barcelona
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
08036 Barcelona
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4056 Basel
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TW89GS Brentford
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10154 New York
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92284 Courbevoie
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