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Enhancing Ultrasound and PHOtoacoustics for Recognition of Intestinal Abnormalities

Objective

EUPHORIA will pave the way to establish MSOT (Multispectral Optoacoustic Tomography) technology for the non-invasive assessment of intestinal inflammation in patients. EUPHORIA will enable commercialization of the technology by finalizing technical improvements that will increase diagnostic outcome beyond what has been shown in a first feasibility study, will improve usability, prepare CE marking for the new device and validate clinical results in a large clinical study.
Inflammatory bowel disease (IBD) is a chronic condition, posing significant burden to patients and health care systems. Patients suffer from a relapsing course of intestinal inflammation, and to date, there is no satisfying non-invasive diagnostic modality for monitoring disease activity. In a recent clinical study conducted by University Hospital Erlangen, MSOT, a technology developed by iThera Medical (ITM), has proven to be superior in diagnostic performance to other procedures.
Imasonic (IMA) and RayFos (RFO) are ideally positioned to drive the technical improvement steps: Imasonic, an expert in ultrasound transducer manufacturing, will develop an ultrasound detector with higher signal-to-noise ratio to enable better sensitivity and detection at depth. RayFos specializes on real-time sensing and image inversion, processing and rendering and has significant experience in optoacoustic tomography algorithms and implementation. iThera Medical will lead the incorporation into the device, CE marking and commercialization. The University Hospital Erlangen is an excellence center in IBD and will drive the clinical validation. Pintail has extensive project management, dissemination and commercialization expertise.
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Coordinator

ITHERA MEDICAL GMBH

Address

Zielstattstrasse 13
81379 Munchen

Germany

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

EU Contribution

€ 887 541,38

Participants (4)

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IMASONIC SAS

France

EU Contribution

€ 305 375

RAYFOS LTD

United Kingdom

EU Contribution

€ 206 150

UNIVERSITATSKLINIKUM ERLANGEN

Germany

EU Contribution

€ 748 998,75

PINTAIL LTD

Ireland

EU Contribution

€ 166 250

Project information

Grant agreement ID: 830965

Status

Ongoing project

  • Start date

    1 January 2019

  • End date

    31 December 2021

Funded under:

H2020-EU.3.

H2020-EU.2.1.

  • Overall budget:

    € 2 985 165

  • EU contribution

    € 2 314 315,13

Coordinated by:

ITHERA MEDICAL GMBH

Germany