Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds

Project description

Novel testing methods for metabolism-disrupting chemicals

Metabolism-disrupting chemicals (MDCs) are natural and anthropogenic chemicals that disrupt the metabolism and ultimately result in obesity and diabetes. The EU-funded GOLIATH project aims to develop an integrated approach for testing and assessing MDCs. Researchers will focus on the main cellular targets of metabolic disruption and develop predictive models as well as toxicity screening assays. Combined with omics data, these tools will help decipher the endocrine mode of action and the adverse effects of MDCs on human health. The GOLIATH test methods have the potential to be exploited for regulatory use, leading to much anticipated guidelines.

Fields of science

• medical and health sciences › clinical medicine › endocrinology
• natural sciences › biological sciences › molecular biology

Programme(s)

• H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme
• H2020-EU.3.1.1. - Understanding health, wellbeing and disease

Topic(s)

• SC1-BHC-27-2018 - New testing and screening methods to identify endocrine disrupting chemicals

Call for proposal

H2020-SC1-BHC-2018-2020

See other projects for this call

Sub call

H2020-SC1-2018-Single-Stage-RTD

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITEIT UTRECHT

Net EU contribution

€ 1 268 269,88

Address

Heidelberglaan 8
3584 CS Utrecht
Netherlands

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

West-Nederland › Utrecht › Utrecht

Participants (15)

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT

France

Net EU contribution

€ 798 786,25

Address

147 Rue De L'universite
75007 Paris Cedex 07

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Ile-de-France › Ile-de-France › Paris

Department of Health

United Kingdom

Net EU contribution

€ 459 104,53

Address

Quarry House, Quarry Hill
LS2 7UE Leeds

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Yorkshire and the Humber › West Yorkshire › Leeds

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Net EU contribution

€ 1 077 695,00

Address

Rue De Tolbiac 101
75654 Paris

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Ile-de-France › Ile-de-France › Paris

KAROLINSKA INSTITUTET

Sweden

Net EU contribution

€ 402 500,00

Address

Nobels Vag 5
17177 Stockholm

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Östra Sverige › Stockholm › Stockholms län

UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE

Spain

Net EU contribution

€ 672 862,50

Address

Avenida De La Universidad S-n
03202 Elche

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Alicante/Alacant › Comunitat Valenciana

AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL

France

Net EU contribution

€ 134 250,00

Address

14 Rue Pierre Et Marie Curie
94700 Maisons Alfort

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Ile-de-France › Ile-de-France › Val-de-Marne

LINKOPINGS UNIVERSITET

Sweden

Net EU contribution

€ 338 287,50

Address

Campus Valla
581 83 Linkoping

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Östra Sverige › Östra Mellansverige › Östergötlands län

VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.

Belgium

Net EU contribution

€ 137 510,00

Address

Boeretang 200
2400 Mol

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Vlaams Gewest › Prov. Antwerpen › Arr. Turnhout

BRUNEL UNIVERSITY LONDON

United Kingdom

Net EU contribution

€ 261 946,25

Address

Kingston Lane
UB8 3PH Uxbridge

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

London › Outer London — West and North West › Harrow and Hillingdon

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

Participation ended

United Kingdom

Net EU contribution

€ 0,00

Address

Trinity Lane The Old Schools
CB2 1TN Cambridge

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

East of England › East Anglia › Cambridgeshire CC

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

United States

Net EU contribution

€ 339 596,84

Address

Franklin Street 1111 12 Floor
94607 Oakland Ca

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

 

BIOPREDIC INTERNATIONAL SARL

France

Net EU contribution

€ 243 750,00

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes

Address

Parc D'activite De La Breteche Batiment A4
35760 Saint Gregoire

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Non-EU contribution

€ 0,00

Region

Bretagne › Bretagne › Ille-et-Vilaine

HOFFMANN SEBASTIAN

Germany

Net EU contribution

€ 75 000,00

Address

Stembergring 15
33106 Paderborn

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Non-EU contribution

€ 0,00

 

 

UMEA UNIVERSITET

Sweden

Net EU contribution

€ 303 750,00

Address

Universitetomradet
901 87 Umea

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Norra Sverige › Övre Norrland › Västerbottens län

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

Net EU contribution

€ 248 525,00

Address

South Kensington Campus Exhibition Road
SW7 2AZ London

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

London › Inner London — West › Westminster